Matches in SemOpenAlex for { <https://semopenalex.org/work/W2528024939> ?p ?o ?g. }
- W2528024939 endingPage "4451" @default.
- W2528024939 startingPage "4436" @default.
- W2528024939 abstract "Methylation is a common and abundant post-translational modification. High-throughput proteomic investigations have reported many methylation sites from complex mixtures of proteins. The lack of consistency between parallel studies, resulting from both false positives and missed identifications, suggests problems with both over-reporting and under-reporting methylation sites. However, isotope labeling can be used effectively to address the issue of false-positives, and fractionation of proteins can increase the probability of identifying methylation sites in lower abundance. Here we have adapted heavy methyl SILAC to analyze fractions of the budding yeast Saccharomyces cerevisiae under respiratory conditions to allow for the production of mitochondria, an organelle whose proteins are often overlooked in larger methyl proteome studies. We have found 12 methylation sites on 11 mitochondrial proteins as well as an additional 14 methylation sites on 9 proteins that are nonmitochondrial. Of these methylation sites, 20 sites have not been previously reported. This study represents the first characterization of the yeast mitochondrial methyl proteome and the second proteomic investigation of global mitochondrial methylation to date in any organism." @default.
- W2528024939 created "2016-10-14" @default.
- W2528024939 creator A5005240902 @default.
- W2528024939 creator A5006474948 @default.
- W2528024939 creator A5012174669 @default.
- W2528024939 creator A5013538296 @default.
- W2528024939 creator A5090650225 @default.
- W2528024939 date "2016-10-18" @default.
- W2528024939 modified "2023-10-15" @default.
- W2528024939 title "Determining the Mitochondrial Methyl Proteome in <i>Saccharomyces cerevisiae</i> using Heavy Methyl SILAC" @default.
- W2528024939 cites W1482772159 @default.
- W2528024939 cites W1484657101 @default.
- W2528024939 cites W1490970026 @default.
- W2528024939 cites W1561252486 @default.
- W2528024939 cites W1561655720 @default.
- W2528024939 cites W1564845388 @default.
- W2528024939 cites W1581820685 @default.
- W2528024939 cites W1588290914 @default.
- W2528024939 cites W1597678601 @default.
- W2528024939 cites W1668458589 @default.
- W2528024939 cites W1729953222 @default.
- W2528024939 cites W1775749144 @default.
- W2528024939 cites W1803102843 @default.
- W2528024939 cites W1811637235 @default.
- W2528024939 cites W1964704790 @default.
- W2528024939 cites W1965243701 @default.
- W2528024939 cites W1966148604 @default.
- W2528024939 cites W1967387437 @default.
- W2528024939 cites W1967790997 @default.
- W2528024939 cites W1974077096 @default.
- W2528024939 cites W1975825529 @default.
- W2528024939 cites W1976358872 @default.
- W2528024939 cites W1977919788 @default.
- W2528024939 cites W1979452711 @default.
- W2528024939 cites W1980509906 @default.
- W2528024939 cites W1986723848 @default.
- W2528024939 cites W1990299806 @default.
- W2528024939 cites W1991123260 @default.
- W2528024939 cites W1994771683 @default.
- W2528024939 cites W1996315419 @default.
- W2528024939 cites W1999032634 @default.
- W2528024939 cites W2000007356 @default.
- W2528024939 cites W2000154625 @default.
- W2528024939 cites W2001118192 @default.
- W2528024939 cites W2002364392 @default.
- W2528024939 cites W2005852281 @default.
- W2528024939 cites W2010182567 @default.
- W2528024939 cites W2010821411 @default.
- W2528024939 cites W2011474450 @default.
- W2528024939 cites W2012441680 @default.
- W2528024939 cites W2013543063 @default.
- W2528024939 cites W2015036156 @default.
- W2528024939 cites W2018062480 @default.
- W2528024939 cites W2018162201 @default.
- W2528024939 cites W2023329023 @default.
- W2528024939 cites W2028673251 @default.
- W2528024939 cites W2037215281 @default.
- W2528024939 cites W2041559788 @default.
- W2528024939 cites W2045892531 @default.
- W2528024939 cites W2047467738 @default.
- W2528024939 cites W2047552911 @default.
- W2528024939 cites W2047611070 @default.
- W2528024939 cites W2048418221 @default.
- W2528024939 cites W2048461817 @default.
- W2528024939 cites W2049491272 @default.
- W2528024939 cites W2053943711 @default.
- W2528024939 cites W2060739737 @default.
- W2528024939 cites W2060882402 @default.
- W2528024939 cites W2063048494 @default.
- W2528024939 cites W2064148432 @default.
- W2528024939 cites W2064969549 @default.
- W2528024939 cites W2065301423 @default.
- W2528024939 cites W2065863562 @default.
- W2528024939 cites W2067031913 @default.
- W2528024939 cites W2067376200 @default.
- W2528024939 cites W2069208897 @default.
- W2528024939 cites W2070451758 @default.
- W2528024939 cites W2071338683 @default.
- W2528024939 cites W2073371472 @default.
- W2528024939 cites W2073567546 @default.
- W2528024939 cites W2074972885 @default.
- W2528024939 cites W2078239448 @default.
- W2528024939 cites W2079125529 @default.
- W2528024939 cites W2080003290 @default.
- W2528024939 cites W2081709323 @default.
- W2528024939 cites W2083523651 @default.
- W2528024939 cites W2084073267 @default.
- W2528024939 cites W2084300920 @default.
- W2528024939 cites W2084900854 @default.
- W2528024939 cites W2085289028 @default.
- W2528024939 cites W2085450186 @default.
- W2528024939 cites W2086671638 @default.
- W2528024939 cites W2088806699 @default.
- W2528024939 cites W2091921454 @default.
- W2528024939 cites W2092368988 @default.
- W2528024939 cites W2093296896 @default.
- W2528024939 cites W2094981306 @default.
- W2528024939 cites W2096057003 @default.