Matches in SemOpenAlex for { <https://semopenalex.org/work/W2528191503> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2528191503 abstract "BackgroundDementia with Lewy bodies (DLB) is a common form of dementia. The presence of Alzheimer's disease (AD) pathology modifies the clinical features of DLB, making it harder to distinguish DLB from AD clinically during life. Our aim was to determine, in a series of patients with dementia in whom autopsy confirmation of diagnosis is available, whether functional imaging of the nigrostriatal pathway improves the accuracy of diagnosis compared to diagnosis by means of clinical criteria alone.MethodsA SPECT scan was carried out with a dopaminergic pre-synaptic ligand [123I]-2beta-carbometoxy-3beta- (4-iodophenyl)-N- (3-fluoropropyl) nortropane (FP-CIT) on a group of patients with a clinical diagnosis of DLB or other dementia. An abnormal scan was defined as one in which right and left posterior putamen binding, measured semi-quantitatively, was more than 2 standard deviations below the mean of the controls.ResultsOver a ten year period it has been possible to collect twenty patients who have been followed from the time of first assessment and time of scan through to death and subsequent detailed neuropathological autopsy. Eight patients fulfilled neuropathological diagnostic criteria for DLB. Nine patients had AD, mostly with co-existing cerebrovascular disease. Three patients had other diagnoses. The sensitivity of the FP-CIT scan for the diagnosis.ConclusionsFP-CIT SPET scans substantially enhanced the accuracy of diagnosis of DLB by comparison with clinical criteria alone." @default.
- W2528191503 created "2016-10-14" @default.
- W2528191503 creator A5040125035 @default.
- W2528191503 date "2007-12-06" @default.
- W2528191503 modified "2023-09-23" @default.
- W2528191503 title "Dementia with Lewy bodies: A comparison of clinical diagnosis, DaTSCAN imaging and neuropathological diagnosis" @default.
- W2528191503 hasPublicationYear "2007" @default.
- W2528191503 type Work @default.
- W2528191503 sameAs 2528191503 @default.
- W2528191503 citedByCount "0" @default.
- W2528191503 crossrefType "journal-article" @default.
- W2528191503 hasAuthorship W2528191503A5040125035 @default.
- W2528191503 hasConcept C126322002 @default.
- W2528191503 hasConcept C126838900 @default.
- W2528191503 hasConcept C142724271 @default.
- W2528191503 hasConcept C187212893 @default.
- W2528191503 hasConcept C2778548049 @default.
- W2528191503 hasConcept C2779097696 @default.
- W2528191503 hasConcept C2779134260 @default.
- W2528191503 hasConcept C2779483572 @default.
- W2528191503 hasConcept C2779504383 @default.
- W2528191503 hasConcept C2779714222 @default.
- W2528191503 hasConcept C2983449737 @default.
- W2528191503 hasConcept C2989005 @default.
- W2528191503 hasConcept C3020647687 @default.
- W2528191503 hasConcept C534262118 @default.
- W2528191503 hasConcept C71924100 @default.
- W2528191503 hasConceptScore W2528191503C126322002 @default.
- W2528191503 hasConceptScore W2528191503C126838900 @default.
- W2528191503 hasConceptScore W2528191503C142724271 @default.
- W2528191503 hasConceptScore W2528191503C187212893 @default.
- W2528191503 hasConceptScore W2528191503C2778548049 @default.
- W2528191503 hasConceptScore W2528191503C2779097696 @default.
- W2528191503 hasConceptScore W2528191503C2779134260 @default.
- W2528191503 hasConceptScore W2528191503C2779483572 @default.
- W2528191503 hasConceptScore W2528191503C2779504383 @default.
- W2528191503 hasConceptScore W2528191503C2779714222 @default.
- W2528191503 hasConceptScore W2528191503C2983449737 @default.
- W2528191503 hasConceptScore W2528191503C2989005 @default.
- W2528191503 hasConceptScore W2528191503C3020647687 @default.
- W2528191503 hasConceptScore W2528191503C534262118 @default.
- W2528191503 hasConceptScore W2528191503C71924100 @default.
- W2528191503 hasLocation W25281915031 @default.
- W2528191503 hasOpenAccess W2528191503 @default.
- W2528191503 hasPrimaryLocation W25281915031 @default.
- W2528191503 hasRelatedWork W1905755800 @default.
- W2528191503 hasRelatedWork W2009413921 @default.
- W2528191503 hasRelatedWork W2011517470 @default.
- W2528191503 hasRelatedWork W2019528241 @default.
- W2528191503 hasRelatedWork W2019650985 @default.
- W2528191503 hasRelatedWork W2069393133 @default.
- W2528191503 hasRelatedWork W2121179979 @default.
- W2528191503 hasRelatedWork W2154498815 @default.
- W2528191503 hasRelatedWork W2158716789 @default.
- W2528191503 hasRelatedWork W2166263576 @default.
- W2528191503 hasRelatedWork W2262890673 @default.
- W2528191503 hasRelatedWork W2270344389 @default.
- W2528191503 hasRelatedWork W2508638789 @default.
- W2528191503 hasRelatedWork W2736405423 @default.
- W2528191503 hasRelatedWork W2746845164 @default.
- W2528191503 hasRelatedWork W2912814323 @default.
- W2528191503 hasRelatedWork W2941663043 @default.
- W2528191503 hasRelatedWork W3042738058 @default.
- W2528191503 hasRelatedWork W3173832229 @default.
- W2528191503 hasRelatedWork W2186821491 @default.
- W2528191503 isParatext "false" @default.
- W2528191503 isRetracted "false" @default.
- W2528191503 magId "2528191503" @default.
- W2528191503 workType "article" @default.