FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2528280320> ?p ?o ?g. }

• W2528280320 endingPage "1470" @default.
• W2528280320 startingPage "1462" @default.
• W2528280320 abstract "The aim of this study was to assess if residential radon exposure might cause EGFR mutations or ALK rearrangements in never-smokers. We designed a multicentre case–control study in a radon-prone area (Galicia, Spain); only lung cancer cases were included in the study. We obtained residential radon measurements and clinical information for all the participants. We compared the median values of residential radon between patients with EGFR mutations or ALK rearrangements versus those without them. 323 patients were included. Median age was 70 years and 19.5% were males. 42 and 15% of patients were EGFR - and ALK -positive, respectively. The most frequent EGFR alterations were exon 19 deletions and exon 21 (L858R) single-point substitution mutations. ALK -positive patients were 10 years younger than ALK -negative patients. Residential radon levels were two-fold higher in patients with exon 19 deletions compared with patients with exon 21 (L858R) single-point substitution mutations (216 versus 118 Bq·m −3 ; p=0.057). There were no differences in residential radon levels by EGFR mutation status. ALK -positive patients (n=12) essentially had two-fold residential radon levels compared with ALK -negative patients (290 versus 164 Bq·m −3 , respectively). Residential radon may have a role in the molecular signature of lung cancer in never-smokers, although more studies with larger sample sizes are needed to support this hypothesis." @default.
• W2528280320 created "2016-10-14" @default.
• W2528280320 creator A5008075602 @default.
• W2528280320 creator A5015881248 @default.
• W2528280320 creator A5020730045 @default.
• W2528280320 creator A5022943285 @default.
• W2528280320 creator A5030217250 @default.
• W2528280320 creator A5034739568 @default.
• W2528280320 creator A5035138222 @default.
• W2528280320 creator A5037602282 @default.
• W2528280320 creator A5038742959 @default.
• W2528280320 creator A5044644602 @default.
• W2528280320 creator A5050569417 @default.
• W2528280320 creator A5055589893 @default.
• W2528280320 creator A5069263136 @default.
• W2528280320 creator A5070557489 @default.
• W2528280320 creator A5077069963 @default.
• W2528280320 creator A5077416833 @default.
• W2528280320 creator A5078970648 @default.
• W2528280320 creator A5085499011 @default.
• W2528280320 creator A5087089783 @default.
• W2528280320 date "2016-10-06" @default.
• W2528280320 modified "2023-10-18" @default.
• W2528280320 title "Residential radon, <i>EGFR</i> mutations and <i>ALK</i> alterations in never-smoking lung cancer cases" @default.
• W2528280320 cites W1525117983 @default.
• W2528280320 cites W1971272757 @default.
• W2528280320 cites W1973826378 @default.
• W2528280320 cites W1979704902 @default.
• W2528280320 cites W1996213693 @default.
• W2528280320 cites W2002816468 @default.
• W2528280320 cites W2003118915 @default.
• W2528280320 cites W2012248028 @default.
• W2528280320 cites W2028965159 @default.
• W2528280320 cites W2041992600 @default.
• W2528280320 cites W2050249255 @default.
• W2528280320 cites W2054353483 @default.
• W2528280320 cites W2057311788 @default.
• W2528280320 cites W2057877600 @default.
• W2528280320 cites W2057960674 @default.
• W2528280320 cites W2095618958 @default.
• W2528280320 cites W2097757428 @default.
• W2528280320 cites W2097951779 @default.
• W2528280320 cites W2100553071 @default.
• W2528280320 cites W2104830962 @default.
• W2528280320 cites W2112850044 @default.
• W2528280320 cites W2113841146 @default.
• W2528280320 cites W2126425813 @default.
• W2528280320 cites W2132611552 @default.
• W2528280320 cites W2134842059 @default.
• W2528280320 cites W2156246679 @default.
• W2528280320 cites W2157010250 @default.
• W2528280320 cites W2239287815 @default.
• W2528280320 cites W2917837889 @default.
• W2528280320 doi "https://doi.org/10.1183/13993003.00407-2016" @default.
• W2528280320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27799390" @default.
• W2528280320 hasPublicationYear "2016" @default.
• W2528280320 type Work @default.
• W2528280320 sameAs 2528280320 @default.
• W2528280320 citedByCount "29" @default.
• W2528280320 countsByYear W25282803202016 @default.
• W2528280320 countsByYear W25282803202017 @default.
• W2528280320 countsByYear W25282803202018 @default.
• W2528280320 countsByYear W25282803202019 @default.
• W2528280320 countsByYear W25282803202020 @default.
• W2528280320 countsByYear W25282803202021 @default.
• W2528280320 countsByYear W25282803202022 @default.
• W2528280320 countsByYear W25282803202023 @default.
• W2528280320 crossrefType "journal-article" @default.
• W2528280320 hasAuthorship W2528280320A5008075602 @default.
• W2528280320 hasAuthorship W2528280320A5015881248 @default.
• W2528280320 hasAuthorship W2528280320A5020730045 @default.
• W2528280320 hasAuthorship W2528280320A5022943285 @default.
• W2528280320 hasAuthorship W2528280320A5030217250 @default.
• W2528280320 hasAuthorship W2528280320A5034739568 @default.
• W2528280320 hasAuthorship W2528280320A5035138222 @default.
• W2528280320 hasAuthorship W2528280320A5037602282 @default.
• W2528280320 hasAuthorship W2528280320A5038742959 @default.
• W2528280320 hasAuthorship W2528280320A5044644602 @default.
• W2528280320 hasAuthorship W2528280320A5050569417 @default.
• W2528280320 hasAuthorship W2528280320A5055589893 @default.
• W2528280320 hasAuthorship W2528280320A5069263136 @default.
• W2528280320 hasAuthorship W2528280320A5070557489 @default.
• W2528280320 hasAuthorship W2528280320A5077069963 @default.
• W2528280320 hasAuthorship W2528280320A5077416833 @default.
• W2528280320 hasAuthorship W2528280320A5078970648 @default.
• W2528280320 hasAuthorship W2528280320A5085499011 @default.
• W2528280320 hasAuthorship W2528280320A5087089783 @default.
• W2528280320 hasBestOaLocation W25282803201 @default.
• W2528280320 hasConcept C104317684 @default.
• W2528280320 hasConcept C121332964 @default.
• W2528280320 hasConcept C126322002 @default.
• W2528280320 hasConcept C143998085 @default.
• W2528280320 hasConcept C176944494 @default.
• W2528280320 hasConcept C2776256026 @default.
• W2528280320 hasConcept C2777714996 @default.
• W2528280320 hasConcept C36823959 @default.
• W2528280320 hasConcept C501734568 @default.
• W2528280320 hasConcept C54355233 @default.

• next