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- W2528388045 abstract "Type 1 diabetes (T1D) is an autoimmune disease characterized by the selective destruction of the insulin-producing beta cells. Beta cell dysfunction caused by an inflammatory microenvironment is believed to trigger the peripheral activation of CD4 and CD8 autoreactive T cells. This review will compile post-transcriptional and post-translational modifications (PTM) involved in the generation of beta cell neoantigens and proposes a reconstruction of the sequence of events connecting environmental changes and autoimmunity." @default.
- W2528388045 created "2016-10-14" @default.
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- W2528388045 date "2016-12-01" @default.
- W2528388045 modified "2023-09-27" @default.
- W2528388045 title "A roadmap of the generation of neoantigens as targets of the immune system in type 1 diabetes" @default.
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- W2528388045 doi "https://doi.org/10.1016/j.coi.2016.09.007" @default.
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