Matches in SemOpenAlex for { <https://semopenalex.org/work/W2528649443> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2528649443 endingPage "620" @default.
- W2528649443 startingPage "615" @default.
- W2528649443 abstract "To evaluate histopathologically the radioprotective effect of L-carnitine on the colonic mucosa in rats undergoing abdominopelvic irradiation.Thirty-two rats were randomly assigned to four experimental groups: intraperitoneal administration of normal saline (group 1) or L-carnitine (300 mL/kg; group 2), followed in groups 3 and 4, respectively, by one dose of abdominopelvic radiation (20 Gy) 30 min later. Rats were sacrificed 5 days after radiation, and their descending colons were resected for histopathological evaluation of the presence and severity of damage.Average damage scores did not differ significantly between groups 1 and 2 (0.13 ± 0.35 and 0.25 ± 0.46, respectively); the group 3 score was highest (10.25 ± 0.71), and the group 4 score (3.63 ± 1.41) was significantly lower than that of group 3 (both p = 0.0001). Pre-radiation L-carnitine administration significantly reduced mucosal thinning, crypt distortion, reactive atypia, inflammation, cryptitis, and reactive lymph-node hyperplasia (all p < 0.01).L-carnitine had a radioprotective effect on rat colonic mucosa. L-carnitine use should be explored for patients with gastrointestinal cancer, who have reduced serum L-carnitine levels." @default.
- W2528649443 created "2016-10-14" @default.
- W2528649443 creator A5010620622 @default.
- W2528649443 creator A5011975596 @default.
- W2528649443 creator A5020479295 @default.
- W2528649443 creator A5032883349 @default.
- W2528649443 creator A5052533814 @default.
- W2528649443 creator A5085593031 @default.
- W2528649443 date "2016-09-01" @default.
- W2528649443 modified "2023-10-14" @default.
- W2528649443 title "L-carnitine has a protective effect on the colonic mucosa during abdominopelvic radiotherapy in rats" @default.
- W2528649443 cites W1531316072 @default.
- W2528649443 cites W1555289727 @default.
- W2528649443 cites W1746204122 @default.
- W2528649443 cites W1969626495 @default.
- W2528649443 cites W1971854573 @default.
- W2528649443 cites W1975234001 @default.
- W2528649443 cites W1994485489 @default.
- W2528649443 cites W1996174246 @default.
- W2528649443 cites W2000656455 @default.
- W2528649443 cites W2002379468 @default.
- W2528649443 cites W2003899546 @default.
- W2528649443 cites W2020391654 @default.
- W2528649443 cites W2022311135 @default.
- W2528649443 cites W2024451372 @default.
- W2528649443 cites W2039764772 @default.
- W2528649443 cites W2051238853 @default.
- W2528649443 cites W2064298774 @default.
- W2528649443 cites W2069901637 @default.
- W2528649443 cites W2073753460 @default.
- W2528649443 cites W2080709742 @default.
- W2528649443 cites W2080927541 @default.
- W2528649443 cites W2081612069 @default.
- W2528649443 cites W2111651157 @default.
- W2528649443 cites W2153688304 @default.
- W2528649443 cites W2155404224 @default.
- W2528649443 cites W2163142557 @default.
- W2528649443 cites W48493471 @default.
- W2528649443 doi "https://doi.org/10.1590/s0102-865020160090000007" @default.
- W2528649443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27737347" @default.
- W2528649443 hasPublicationYear "2016" @default.
- W2528649443 type Work @default.
- W2528649443 sameAs 2528649443 @default.
- W2528649443 citedByCount "1" @default.
- W2528649443 countsByYear W25286494432020 @default.
- W2528649443 crossrefType "journal-article" @default.
- W2528649443 hasAuthorship W2528649443A5010620622 @default.
- W2528649443 hasAuthorship W2528649443A5011975596 @default.
- W2528649443 hasAuthorship W2528649443A5020479295 @default.
- W2528649443 hasAuthorship W2528649443A5032883349 @default.
- W2528649443 hasAuthorship W2528649443A5052533814 @default.
- W2528649443 hasAuthorship W2528649443A5085593031 @default.
- W2528649443 hasBestOaLocation W25286494431 @default.
- W2528649443 hasConcept C126322002 @default.
- W2528649443 hasConcept C142724271 @default.
- W2528649443 hasConcept C2777397205 @default.
- W2528649443 hasConcept C2778435403 @default.
- W2528649443 hasConcept C2781283455 @default.
- W2528649443 hasConcept C509974204 @default.
- W2528649443 hasConcept C71924100 @default.
- W2528649443 hasConcept C90924648 @default.
- W2528649443 hasConceptScore W2528649443C126322002 @default.
- W2528649443 hasConceptScore W2528649443C142724271 @default.
- W2528649443 hasConceptScore W2528649443C2777397205 @default.
- W2528649443 hasConceptScore W2528649443C2778435403 @default.
- W2528649443 hasConceptScore W2528649443C2781283455 @default.
- W2528649443 hasConceptScore W2528649443C509974204 @default.
- W2528649443 hasConceptScore W2528649443C71924100 @default.
- W2528649443 hasConceptScore W2528649443C90924648 @default.
- W2528649443 hasIssue "9" @default.
- W2528649443 hasLocation W25286494431 @default.
- W2528649443 hasLocation W25286494432 @default.
- W2528649443 hasLocation W25286494433 @default.
- W2528649443 hasLocation W25286494434 @default.
- W2528649443 hasOpenAccess W2528649443 @default.
- W2528649443 hasPrimaryLocation W25286494431 @default.
- W2528649443 hasRelatedWork W2021771973 @default.
- W2528649443 hasRelatedWork W2022944059 @default.
- W2528649443 hasRelatedWork W2070138482 @default.
- W2528649443 hasRelatedWork W2112232161 @default.
- W2528649443 hasRelatedWork W2146211406 @default.
- W2528649443 hasRelatedWork W2168923614 @default.
- W2528649443 hasRelatedWork W2384708512 @default.
- W2528649443 hasRelatedWork W2428341374 @default.
- W2528649443 hasRelatedWork W3038666778 @default.
- W2528649443 hasRelatedWork W4253632170 @default.
- W2528649443 hasVolume "31" @default.
- W2528649443 isParatext "false" @default.
- W2528649443 isRetracted "false" @default.
- W2528649443 magId "2528649443" @default.
- W2528649443 workType "article" @default.