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- W2528752018 abstract "The synthesis of several monomeric and dimeric steroidal [1,2,4]triazolo[1,5-a]pyrimidines (TPs) derived from steroids are described. These derivatives were prepared from α,β-unsaturated carbonyl compounds through a Claisen Schmidt condensation and rearrangement of the spiro moiety followed by a cycloaddition with 3-amino-1,2,4-triazole. The antiproliferative activity of compounds 7, 13-15 was tested against human cancer cells; several IG50 values were below 10μM." @default.
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- W2528752018 date "2016-12-01" @default.
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- W2528752018 title "Synthesis of monomeric and dimeric steroids containing [1,2,4]triazolo[1,5-a]pyrimidines" @default.
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- W2528752018 doi "https://doi.org/10.1016/j.steroids.2016.09.014" @default.
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