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- W2528852008 abstract "Carbohydrate-binding modules (CBMs) are found in many carbohydrate-active enzymes. CBMs bind to a range of polysaccharides, their primary function be- ing to increase the catalytic efficiency of the carbohy- drate-active enzymes against soluble and/or insoluble substrates. CBMs bind to their target ligands with high specificities and affinities. Thus, CBM systems are excel- lent models to study the mechanism of protein-carbohy- drate interaction. To date, CBMs have been classified into 45 different families and many structural and functional studies have been reported. At present, three-dimensional structures of CBMs from 31 different families have been determined. These structures demonstrate that the fold most commonly found in CBMs is the β-sandwich. In the past few years, about 10 new structures from different families have been reported. These enable detailed clas- sification of CBM structures. This article reviews recent structural and functional studies of CBMs and discusses the sub-classification of β-sandwich CBMs." @default.
- W2528852008 created "2016-10-14" @default.
- W2528852008 creator A5075427398 @default.
- W2528852008 date "2006-01-01" @default.
- W2528852008 modified "2023-09-26" @default.
- W2528852008 title "Review Recent structural studies of carbohydrate-binding modules" @default.
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