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- W2529074512 abstract "Abstract Mosquitoes are vectors for multiple infectious human diseases and use a variety of sensory cues (olfactory, temperature, humidity and visual) to locate a human host. A comprehensive understanding of the circuitry underlying sensory signalling in the mosquito brain is lacking. Here we used the Q-system of binary gene expression to develop transgenic lines of Anopheles gambiae in which olfactory receptor neurons expressing the odorant receptor co-receptor ( Orco ) gene are labelled with GFP. These neurons project from the antennae and maxillary palps to the antennal lobe (AL) and from the labella on the proboscis to the suboesophageal zone (SEZ), suggesting integration of olfactory and gustatory signals occurs in this brain region. We present detailed anatomical maps of olfactory innervations in the AL and the SEZ, identifying glomeruli that may respond to human body odours or carbon dioxide. Our results pave the way for anatomical and functional neurogenetic studies of sensory processing in mosquitoes." @default.
- W2529074512 created "2016-10-14" @default.
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- W2529074512 date "2016-10-03" @default.
- W2529074512 modified "2023-10-15" @default.
- W2529074512 title "Organization of olfactory centres in the malaria mosquito Anopheles gambiae" @default.
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- W2529074512 doi "https://doi.org/10.1038/ncomms13010" @default.
- W2529074512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5063964" @default.
- W2529074512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27694947" @default.
- W2529074512 hasPublicationYear "2016" @default.
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