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- W2529128072 endingPage "2961" @default.
- W2529128072 startingPage "2944" @default.
- W2529128072 abstract "Phosphatases play key roles in normal physiology and diseases. Studying phosphatases has been both essential and challenging, and the application of conventional genetic and biochemical methods has led to crucial but still limited understanding of their mechanisms, substrates, and exclusive functions within highly intricate networks. With the advances in technologies such as cellular imaging and molecular and chemical biology in terms of sensitive tools and methods, the phosphatase field has thrived in the past years and has set new insights for cell signaling studies and for therapeutic development. In this review, we give an overview of the existing interdisciplinary tools for phosphatases, give examples on how they have been applied to increase our understanding of these enzymes, and suggest how they-and other tools yet barely used in the phosphatase field-might be adapted to address future questions and challenges." @default.
- W2529128072 created "2016-10-14" @default.
- W2529128072 creator A5018426466 @default.
- W2529128072 creator A5055181051 @default.
- W2529128072 creator A5085340132 @default.
- W2529128072 date "2016-10-04" @default.
- W2529128072 modified "2023-10-02" @default.
- W2529128072 title "Approaches to Study Phosphatases" @default.
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