FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2529323341> ?p ?o ?g. }

• W2529323341 abstract "In proteomic studies, poor detection of low abundant proteins is a major problem due to the presence of highly abundant proteins. Therefore, the specific removal or depletion of highly abundant proteins prior to analysis is necessary. In response to this problem, a series of pH-sensitive functional mesoporous silica materials composed of 2-(diethylamino)ethyl methacrylate and methacrylic acid units were designed and synthesized via atom transfer radical polymerization. These functional mesoporous silica materials were characterized and their ability for adsorption and separation of proteins was evaluated. Possessing a pH-sensitive feature, the synthesized functional materials showed selective adsorption of some proteins in aqueous or buffer solutions at certain pH values. The specific removal of a particular protein from a mixed protein solution was subsequently studied. The analytical results confirmed that all the target proteins (bovine serum albumin, ovalbumin, and lysozyme) can be removed by the proposed materials from a five-protein mixture in a single operation. Finally, the practical application of this approach was also evaluated by the selective removal of certain proteins from real biological samples. The results revealed that the maximum removal efficiencies of ovalbumin and lysozyme from egg white sample were obtained as 99% and 92%, respectively, while the maximum removal efficiency of human serum albumin from human serum sample was about 80% by the proposed method. It suggested that this treatment process reduced the complexity of real biological samples and facilitated the identification of hidden proteins in chromatograms." @default.
• W2529323341 created "2016-10-14" @default.
• W2529323341 creator A5003537990 @default.
• W2529323341 creator A5004349988 @default.
• W2529323341 creator A5013509330 @default.
• W2529323341 creator A5035590977 @default.
• W2529323341 creator A5075974788 @default.
• W2529323341 date "2017-01-01" @default.
• W2529323341 modified "2023-10-16" @default.
• W2529323341 title "Fabrication of diverse pH-sensitive functional mesoporous silica for selective removal or depletion of highly abundant proteins from biological samples" @default.
• W2529323341 cites W1016107859 @default.
• W2529323341 cites W1033829746 @default.
• W2529323341 cites W1780545990 @default.
• W2529323341 cites W1945767359 @default.
• W2529323341 cites W1963953414 @default.
• W2529323341 cites W1965688885 @default.
• W2529323341 cites W1966417606 @default.
• W2529323341 cites W1967102831 @default.
• W2529323341 cites W1968547128 @default.
• W2529323341 cites W1975109967 @default.
• W2529323341 cites W1975712870 @default.
• W2529323341 cites W1986100784 @default.
• W2529323341 cites W1989029452 @default.
• W2529323341 cites W1996195941 @default.
• W2529323341 cites W1996721996 @default.
• W2529323341 cites W2001594257 @default.
• W2529323341 cites W2003856466 @default.
• W2529323341 cites W2010625987 @default.
• W2529323341 cites W2010757380 @default.
• W2529323341 cites W2013234359 @default.
• W2529323341 cites W2018982882 @default.
• W2529323341 cites W2027802965 @default.
• W2529323341 cites W2036640151 @default.
• W2529323341 cites W2052811691 @default.
• W2529323341 cites W2057141233 @default.
• W2529323341 cites W2060447725 @default.
• W2529323341 cites W2060826413 @default.
• W2529323341 cites W2068521408 @default.
• W2529323341 cites W2068738612 @default.
• W2529323341 cites W2068958063 @default.
• W2529323341 cites W2069036831 @default.
• W2529323341 cites W2072845924 @default.
• W2529323341 cites W2082866189 @default.
• W2529323341 cites W2087658145 @default.
• W2529323341 cites W2091102516 @default.
• W2529323341 cites W2092494155 @default.
• W2529323341 cites W2120842722 @default.
• W2529323341 cites W2135707926 @default.
• W2529323341 cites W2156041841 @default.
• W2529323341 cites W2160793400 @default.
• W2529323341 cites W6162489 @default.
• W2529323341 cites W757997095 @default.
• W2529323341 doi "https://doi.org/10.1016/j.talanta.2016.10.003" @default.
• W2529323341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27837845" @default.
• W2529323341 hasPublicationYear "2017" @default.
• W2529323341 type Work @default.
• W2529323341 sameAs 2529323341 @default.
• W2529323341 citedByCount "7" @default.
• W2529323341 countsByYear W25293233412018 @default.
• W2529323341 countsByYear W25293233412019 @default.
• W2529323341 crossrefType "journal-article" @default.
• W2529323341 hasAuthorship W2529323341A5003537990 @default.
• W2529323341 hasAuthorship W2529323341A5004349988 @default.
• W2529323341 hasAuthorship W2529323341A5013509330 @default.
• W2529323341 hasAuthorship W2529323341A5035590977 @default.
• W2529323341 hasAuthorship W2529323341A5075974788 @default.
• W2529323341 hasConcept C150394285 @default.
• W2529323341 hasConcept C150539798 @default.
• W2529323341 hasConcept C161790260 @default.
• W2529323341 hasConcept C178790620 @default.
• W2529323341 hasConcept C184651966 @default.
• W2529323341 hasConcept C185592680 @default.
• W2529323341 hasConcept C203014093 @default.
• W2529323341 hasConcept C2776946954 @default.
• W2529323341 hasConcept C2776966407 @default.
• W2529323341 hasConcept C2778597219 @default.
• W2529323341 hasConcept C43617362 @default.
• W2529323341 hasConcept C44228677 @default.
• W2529323341 hasConcept C49853544 @default.
• W2529323341 hasConcept C521977710 @default.
• W2529323341 hasConcept C55493867 @default.
• W2529323341 hasConcept C82776694 @default.
• W2529323341 hasConcept C86803240 @default.
• W2529323341 hasConcept C86807702 @default.
• W2529323341 hasConcept C88001094 @default.
• W2529323341 hasConcept C8891405 @default.
• W2529323341 hasConcept C8985478 @default.
• W2529323341 hasConceptScore W2529323341C150394285 @default.
• W2529323341 hasConceptScore W2529323341C150539798 @default.
• W2529323341 hasConceptScore W2529323341C161790260 @default.
• W2529323341 hasConceptScore W2529323341C178790620 @default.
• W2529323341 hasConceptScore W2529323341C184651966 @default.
• W2529323341 hasConceptScore W2529323341C185592680 @default.
• W2529323341 hasConceptScore W2529323341C203014093 @default.
• W2529323341 hasConceptScore W2529323341C2776946954 @default.
• W2529323341 hasConceptScore W2529323341C2776966407 @default.
• W2529323341 hasConceptScore W2529323341C2778597219 @default.
• W2529323341 hasConceptScore W2529323341C43617362 @default.
• W2529323341 hasConceptScore W2529323341C44228677 @default.
• W2529323341 hasConceptScore W2529323341C49853544 @default.

• next