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- W2529679074 abstract "Multiple sclerosis (MS) is a chronic autoimmune inflammatory demyelinating disorder of the central nervous system (CNS), which causes severe disability and requires extensive medical attention and treatment. While the infiltration of pathogenic immune cells into the CNS leads to the formation of inflammatory lesions in its initial relapsing-remitting stage, late stages of MS are characterized by progressive neuronal loss and demyelination even without continued interaction with the peripheral immune compartment. Several genetic and environmental factors modulate and influence these processes on multiple levels. Genetic variants confer a predisposition for the development of MS, but are not accessible to therapeutic intervention as of today. However, migration studies suggest that environmental factors influence disease development, activity and progression. This article reviews mechanisms of disease pathogenesis in MS and their modulation by environmental factors such as geographical localization, the gut microbiome and the diet." @default.
- W2529679074 created "2016-10-14" @default.
- W2529679074 creator A5001353818 @default.
- W2529679074 creator A5024940233 @default.
- W2529679074 date "2016-12-01" @default.
- W2529679074 modified "2023-10-18" @default.
- W2529679074 title "Environmental control of autoimmune inflammation in the central nervous system" @default.
- W2529679074 cites W10989798 @default.
- W2529679074 cites W1515023627 @default.
- W2529679074 cites W1808548607 @default.
- W2529679074 cites W1826688844 @default.
- W2529679074 cites W1894807755 @default.
- W2529679074 cites W1908756607 @default.
- W2529679074 cites W1914347682 @default.
- W2529679074 cites W1941562583 @default.
- W2529679074 cites W1963769931 @default.
- W2529679074 cites W1967072175 @default.
- W2529679074 cites W1968513811 @default.
- W2529679074 cites W1969682776 @default.
- W2529679074 cites W1974373338 @default.
- W2529679074 cites W1976432505 @default.
- W2529679074 cites W1979713551 @default.
- W2529679074 cites W1979896023 @default.
- W2529679074 cites W1982813749 @default.
- W2529679074 cites W1985106457 @default.
- W2529679074 cites W1996450150 @default.
- W2529679074 cites W2009701030 @default.
- W2529679074 cites W2013234597 @default.
- W2529679074 cites W2014127183 @default.
- W2529679074 cites W2017158862 @default.
- W2529679074 cites W2018668951 @default.
- W2529679074 cites W2021616480 @default.
- W2529679074 cites W2023580852 @default.
- W2529679074 cites W2035103102 @default.
- W2529679074 cites W2037907937 @default.
- W2529679074 cites W2042166711 @default.
- W2529679074 cites W2044216294 @default.
- W2529679074 cites W2056247628 @default.
- W2529679074 cites W2074901168 @default.
- W2529679074 cites W2077196620 @default.
- W2529679074 cites W2077764881 @default.
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- W2529679074 cites W2083770406 @default.
- W2529679074 cites W2085047075 @default.
- W2529679074 cites W2085429548 @default.
- W2529679074 cites W2103529868 @default.
- W2529679074 cites W2105206040 @default.
- W2529679074 cites W2110228129 @default.
- W2529679074 cites W2111553898 @default.
- W2529679074 cites W2112837750 @default.
- W2529679074 cites W2112948254 @default.
- W2529679074 cites W2112999168 @default.
- W2529679074 cites W2116868464 @default.
- W2529679074 cites W2121968767 @default.
- W2529679074 cites W2122509810 @default.
- W2529679074 cites W2134781591 @default.
- W2529679074 cites W2136266325 @default.
- W2529679074 cites W2140118176 @default.
- W2529679074 cites W2142577589 @default.
- W2529679074 cites W2154911070 @default.
- W2529679074 cites W2164331547 @default.
- W2529679074 cites W2166335159 @default.
- W2529679074 cites W2170137456 @default.
- W2529679074 cites W2171571559 @default.
- W2529679074 cites W2176959251 @default.
- W2529679074 cites W2193851668 @default.
- W2529679074 cites W2210325128 @default.
- W2529679074 cites W2212228100 @default.
- W2529679074 cites W2241001812 @default.
- W2529679074 cites W2277622783 @default.
- W2529679074 cites W2279600384 @default.
- W2529679074 cites W2288073912 @default.
- W2529679074 cites W2288478936 @default.
- W2529679074 cites W2293849684 @default.
- W2529679074 cites W2319284141 @default.
- W2529679074 cites W2323516874 @default.
- W2529679074 cites W2345604850 @default.
- W2529679074 cites W2346752870 @default.
- W2529679074 cites W2359274148 @default.
- W2529679074 cites W4211241312 @default.
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- W2529679074 doi "https://doi.org/10.1016/j.coi.2016.09.002" @default.
- W2529679074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5125858" @default.
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