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• W2529839920 abstract "Portal imaging and CBCT are used routinely in breast and lung radiation therapy for setup verification. These systems, however, do not monitor the patient in real time during treatment. There is a commercially available surface guided radiation therapy (SGRT) device that uses stereoscopic video images based on a triangulation approach and a nonrigid algorithm to match the patient’s 3D surface with the reference image. In this work, a Catalyst HD system was used to assess the intrafractional motion error for breast cancer and lung stereotactic body radiation therapy (SBRT) patients. A total of 3089 intrafraction data points from 4 patients with right-sided breast (RB) cancer and 2562 data points from 5 lung SBRT (L-SBRT) patients were obtained and analyzed offline. The percentage of mean errors that fell outside of the threshold of 2 mm, 3 mm, and 5 mm along the translation direction (L-R, S-I, and A-P) were assessed. The systematic (Σ) and random error (σ) were quantified over the course of treatment. The correlation between intrafraction treatment time and mean error of 3D displacement was evaluated using a linear regression method. Deviations of 2 mm, 3 mm, and 5 mm were observed less than 5%, 2%, and 0% of the time, respectively, along the translational axes for RB and L-SBRT patients. The systematics errors were within 0.12 and 0.50 mm for RB patients and between 0.24 and 0.29 mm for L-SBRT patients. The random errors were less than 1.43 and 2.20 mm for RB and L-SBRT patients, respectively. Using the Peterson coefficient, r, the mean error of 3D translational displacement showed significant correlation with treatment time for RB (r=0.69, P=0.001) and L-SBRT (r=0.69, 0.0009) patient. This suggests that longer treatments can lead to larger intrafractional motion error. SGRT can be used to ensure accurate patient positioning during treatment without an additional delivery of dose to the patient. The overall results are within good agreement with reported studies in literature. The study demonstrated the value in reducing the treatment time to lead to a corresponding reduction in intrafraction motion errors." @default.
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• W2529839920 date "2016-10-01" @default.
• W2529839920 modified "2023-09-25" @default.
• W2529839920 title "Three-Dimensional Surface-Guided Radiation Therapy in the Evaluation of Intrafraction Motion for Breast and Lung" @default.
• W2529839920 doi "https://doi.org/10.1016/j.ijrobp.2016.06.2371" @default.
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