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- W2530080859 endingPage "770" @default.
- W2530080859 startingPage "759" @default.
- W2530080859 abstract "A number of disorders cause iron overload: some are of genetic origin, such as hereditary haemochromatosis, while others are acquired, for instance due to repeated transfusions. This article reviews the treatment options for hereditary haemochromatosis, with special attention to the use of erythrocytapheresis. In general, therapy is based on the removal of excess body iron, for which ferritin levels are used to monitor the effectiveness of treatment. For many decades phlebotomy has been widely accepted as the standard treatment. Recent publications suggest that erythrocytapheresis, as a more individualized treatment, can provide a good balance between effectiveness, tolerability and costs. Other treatments like oral chelators and proton pomp inhibitors, which are used in selected patients, create the possibility to further individualize treatment of hereditary haemochromatosis. In the future, hepcidin-targeted therapy could provide a more fundamental approach to treatment." @default.
- W2530080859 created "2016-10-21" @default.
- W2530080859 creator A5002755181 @default.
- W2530080859 creator A5052972003 @default.
- W2530080859 creator A5085106714 @default.
- W2530080859 date "2016-10-10" @default.
- W2530080859 modified "2023-10-04" @default.
- W2530080859 title "How we manage patients with hereditary haemochromatosis" @default.
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- W2530080859 doi "https://doi.org/10.1111/bjh.14376" @default.