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- W2530092009 abstract "No placebo controlled clinical trials evaluating airway clearance techniques have been performed in BC. We evaluate short and long-term efficacy of ELTGOL in BC in a randomized control trial with placebo (Clinical Trial Registration NCT01578681). Non-cystic fibrosis BC adult patients in stable state with > 10 ml sputum/day not practising regular chest physiotherapy were randomized to perform ELTGOL or a placebo exercise twice daily. Patients were assessed at 7 visits (V) over one year. Primary endpoint: sputum volume during the procedure at V2 and 24-h post treatment. Secondary endpoints: sputum volume during the procedure at V7 and 24-h post treatment; Leicester Cough Questionnaire (LCQ), Saint George's Respiratory Questionnaire (SGRQ). Results: 44 patients were randomized (22 ELTGOL group and 22 placebo group; mean age 63.04 ± 13.48 and 67.72 ± 9.08). Sputum volume during the procedure at V2 and 24-h post treatment were higher in the ELTGOL group (12.27 ± 11.92 ml vs. 0 ml and 47.75 ± 31.6 ml vs. 12.04 ± 9.86 ml, p < 0.001). At V7 sputum volume during the procedure and 24-h post treatment were higher in the ELTGOL group (11.07 ± 5.60 ml vs. 0 ml and 45.71 ± 26.30 ml vs. 13.43 ± 7.46 ml, p < 0.001). The ELTGOL group showed a significant improvement in the SGRQ (p < 0.001) andthe LCQ (p < 0.002). Conclusions: The ELTGOL technique is effective in airway clearance both in the short and long term, improves quality of life and reduces the impact of daily cough in non-cystic fibrosis BC adult patients." @default.
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- W2530092009 date "2016-10-11" @default.
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- W2530092009 title "Long-term randomized controlled trial to evaluate the efficacy of low expiration with the open glottis in the lateral posture in bronchiectasis" @default.
- W2530092009 doi "https://doi.org/10.1055/s-0036-1592262" @default.
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