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- W2530216071 abstract "A highly efficient and practical method has been disclosed for the convenient access of structurally diverse 1,4-dihydropyridines via one-pot, four-component reactions of aryl aldehydes, different C−H activated acidic compounds bearing nitrile moiety, dimethyl acetylenedicarboxylate and aromatic/aliphatic amines using piperidine as an effective organo-base catalyst in ethanol at ambient conditions. This domino synthetic strategy proceeded very smoothly and provided immense advantages, including facile operational procedure, excellent product yields, shorter reaction time and applicability to wide range of substrates. This protocol furnishes an alternate route to construct a library of potent DHPs under the shade of green chemistry principle." @default.
- W2530216071 created "2016-10-21" @default.
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- W2530216071 date "2016-10-01" @default.
- W2530216071 modified "2023-10-13" @default.
- W2530216071 title "Piperidine Catalyzed Four-component Strategy for the Facile Access of Polyfunctionalized 1,4-Dihydropyridines at Ambient Conditions" @default.
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- W2530216071 doi "https://doi.org/10.1002/slct.201601358" @default.
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