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• W2530228510 abstract "Manganese (Mn) is an essential metal involved in multiple physiological functions. Environmental exposure to airborne Mn is associated with neurocognitive deficits in humans. Children, whose nervous system is in development, are particularly susceptible to Mn neurotoxicity. The objective of this study was to assess the association between Mn environmental exposure, and effects on visuoperception and visual memory in schoolchildren. We assessed schoolchildren between 7 and 11 years old, with similar socioeconomic status, from the mining district of Molango (n = 148) and Agua Blanca (n = 119, non-mining area) in Hidalgo state, Mexico. The Rey-Osterrieth Complex Figure (ROCF) test was used to assess visuoperception and short-term visual memory. Hair manganese (MnH) concentrations were determined. Linear regression models were constructed to estimate the associations between MnH and ROCF scores, adjusted for potential confounders. The geometric mean MnH was nine times higher in schoolchildren from the Mn mining area (5.25 μg/g) than in schoolchildren from the non-mining area (0.55 μg/g). For the ROCF Copy trial, MnH was significantly associated with an increase in distortion errors (tangency, closure), angle errors, overtracing (partial overtracing). In the Immediate Recall trial, MnH was significantly associated with increased overtracing (partial overtracing) and omissions, and negatively associated with the number of perceptual drawn units, total score and percentage immediate recall. MnH is associated with alterations in visuoperception and short-term visual memory in schoolchildren exposed to airborne Mn." @default.
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• W2530228510 date "2016-12-01" @default.
• W2530228510 modified "2023-10-15" @default.
• W2530228510 title "Effects of manganese exposure on visuoperception and visual memory in schoolchildren" @default.
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• W2530228510 doi "https://doi.org/10.1016/j.neuro.2016.10.006" @default.
• W2530228510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27737811" @default.
• W2530228510 hasPublicationYear "2016" @default.
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