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- W2530477760 endingPage "1723" @default.
- W2530477760 startingPage "1723" @default.
- W2530477760 abstract "Beyond their indispensable role in hemostasis, platelets have shown to affect the development of inflammatory disorders, as they have been epidemiologically and mechanistically linked to diseases featuring an inflammatory reaction in inflammatory diseases like multiple sclerosis, rheumatoid arthritis and inflammatory bowel disorders. The identification of novel molecular mechanisms linking inflammation and to platelets has highlighted them as new targets for therapeutic interventions. In particular, genetic and pharmacological studies have identified an important role for platelets in neuroinflammation. This review summarizes the main molecular links between platelets and inflammation, focusing on immune regulatory factors, receptors, cellular targets and signaling pathways by which they can amplify inflammatory reactions and that make them potential therapeutic targets." @default.
- W2530477760 created "2016-10-21" @default.
- W2530477760 creator A5001410073 @default.
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- W2530477760 creator A5073964612 @default.
- W2530477760 date "2016-10-14" @default.
- W2530477760 modified "2023-10-16" @default.
- W2530477760 title "The Inflammatory Role of Platelets: Translational Insights from Experimental Studies of Autoimmune Disorders" @default.
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