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- W2530705751 startingPage "1539" @default.
- W2530705751 abstract "5′-hydroxymethylcytosine (5hmC) is a variant of the common covalent epigenetic modification of DNA 5′-methylcytosine (5mC). Although the presence of this modified base in mammalian DNA has been recognized for several decades, it has recently gained center stage as a suspected intermediate in enzymatic active demethylation of 5mC. The role of 5hmC remains elusive in spite of a large body of studies. It is proposed that 5hmC is a variant of the 5mC epigenetic signal and is involved in epigenetic regulation of gene function. Recent data support a role for 5hmC in the activation of lineage-specific enhancers." @default.
- W2530705751 created "2016-10-21" @default.
- W2530705751 creator A5007458839 @default.
- W2530705751 date "2016-11-01" @default.
- W2530705751 modified "2023-09-29" @default.
- W2530705751 title "The elusive role of 5′-hydroxymethylcytosine" @default.
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- W2530705751 doi "https://doi.org/10.2217/epi-2016-0076" @default.
- W2530705751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27733056" @default.
- W2530705751 hasPublicationYear "2016" @default.
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