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- W2530867085 abstract "In this study, we determined normal levels of dysferlin expression in CD14+ monocytes by flow cytometry (FC) as a screening tool for dysferlinopathies.Monocytes from 183 healthy individuals and 29 patients were immunolabeled, run on an FACScalibur flow cytometer, and analyzed by FlowJo software.The relative quantity of dysferlin was expressed as mean fluorescence intensity (MFI). Performance of this diagnostic test was assessed by calculating likelihood ratios at different MFI cut-off points, which allowed definition of 4 disease classification groups in a simplified algorithm.The MFI value may differentiate patients with dysferlinopathy from healthy individuals; it may be a useful marker for screening purposes. Muscle Nerve 54: 1064-1071, 2016." @default.
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- W2530867085 date "2016-10-11" @default.
- W2530867085 modified "2023-10-17" @default.
- W2530867085 title "Dysferlin quantification in monocytes for rapid screening for dysferlinopathies" @default.
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- W2530867085 doi "https://doi.org/10.1002/mus.25156" @default.
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