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- W2530978771 abstract "Clinical trials in glioma patients with neurocognitive deficits face challenges due to lacking or unreliable patient self-reports on their health-related quality of life (HRQOL). Patient-proxy data could help solve this issue. We determined whether patient-proxy concordance levels were affected by patients' neurocognitive functioning.Patient and patient-by-proxy HRQOL ratings were assessed via SF-36 and EORTC QLQ-BN20, respectively, in 246 patients. Data on neurocognitive functioning were collected on a subgroup of 195 patients. Patient-proxy agreement was measured using the Bland-Altman limit of agreement, the mean difference, the concordance correlation coefficient (CCC), and the percentage difference (PD, ±0, 5, or 10 points). We defined patients to be cognitively impaired (n = 66) or cognitively intact (n = 129) based on their neurocognitive performance.Patients rated their physical function and general health to be better than their proxies did, while at the same time, patients reported more visual disorders, communication deficits, itchy skin, and problems with bladder control. The cognitively impaired subgroup reported poorer physical functioning, more visual disorders, headaches, itchy skin, and issues with bladder control. In the cognitively intact group, no statistical significant differences were observed between patients and proxies. Not surprisingly, Bland-Altman plots revealed a high agreement between the patient and patient-by-proxy rating in all HRQOL domains ranging from 95 to 99 %. The CCC was fairly high in all HRQOL domains (0.37-0.80), and the percentage of perfect agreement (PD ± 0) ranged from 8.5 to 76.8 %. In the cognitively impaired patients, the mean difference between patients and proxies was overall larger, and accordingly, agreement based on Bland-Altman plots was lower.The level of agreement between patient and patient-by-proxy ratings of low-grade glioma patients' HRQOL is generally high. However, patient-proxy agreement is lower in patients with neurocognitive deficits than in patients without neurocognitive deficits." @default.
- W2530978771 created "2016-10-21" @default.
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- W2530978771 date "2016-10-15" @default.
- W2530978771 modified "2023-10-14" @default.
- W2530978771 title "Impact of neurocognitive deficits on patient–proxy agreement regarding health-related quality of life in low-grade glioma patients" @default.
- W2530978771 cites W1545575598 @default.
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- W2530978771 cites W1968764921 @default.
- W2530978771 cites W1969684282 @default.
- W2530978771 cites W1988420271 @default.
- W2530978771 cites W1991160402 @default.
- W2530978771 cites W1991911445 @default.
- W2530978771 cites W1994769053 @default.
- W2530978771 cites W1995633792 @default.
- W2530978771 cites W1998207473 @default.
- W2530978771 cites W2000006102 @default.
- W2530978771 cites W2000657166 @default.
- W2530978771 cites W2000828587 @default.
- W2530978771 cites W2015699317 @default.
- W2530978771 cites W2015795623 @default.
- W2530978771 cites W2016827321 @default.
- W2530978771 cites W2019866591 @default.
- W2530978771 cites W2025487319 @default.
- W2530978771 cites W2025587609 @default.
- W2530978771 cites W2030059405 @default.
- W2530978771 cites W2033433258 @default.
- W2530978771 cites W2037232743 @default.
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- W2530978771 cites W2096455354 @default.
- W2530978771 cites W2102471539 @default.
- W2530978771 cites W2106431827 @default.
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- W2530978771 doi "https://doi.org/10.1007/s11136-016-1426-z" @default.
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