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- W2531077993 abstract "Cutaneous dirofilariosis is a canine mosquito-borne zoonosis that can cause larva migrans disease in humans. Dirofilaria repens is considered an emerging pathogen occurring with high prevalence in Mediterranean areas and many parts of tropical Asia. In Hong Kong, a second species, Candidatus Dirofilaria hongkongensis, has been reported. The present study aimed to compare mitochondrial genomes from these parasites and to obtain population genetic information.Complete mitochondrial genomes were obtained by PCR and Sanger sequencing or ILLUMINA sequencing for four worms. Cytochrome oxidase subunit 1 sequences identified three as D. repens (all from Europe) and one as C. D. hongkongensis (from India). Mitochondrial genomes have the same organization as in other spirurid nematodes but a higher preference for thymine in the coding strand. Phylogenetic analysis was in contradiction to current taxonomy of the Onchocercidae but in agreement with a recent multi-locus phylogenetic analysis using both mitochondrial and nuclear markers. D. repens and C. D. hongkongensis sequences clustered together and were the common sister group to Dirofilaria immitis. Analysis of a 2.5 kb mitochondrial genome fragment from macrofilaria or canine blood samples from Europe (42), Thailand (2), India (1) and Vietnam (1) revealed only small genetic differences in the D. repens samples including all European and the Vietnam sample. The Indian C. D. hongkongensis and the two Thai samples formed separate clusters and differences were comparatively large.Genetic differences between Dirofilaria spp. causing cutaneous disease can be considerable whereas D. repens itself was genetically quite homogenous. C. D. hongkongensis was identified for the first time from the Indian subcontinent. The full mitochondrial genome sequence strengthens the hypothesis that it represents an independent species and the Thai samples might represent another cryptic species, Candidatus Dirofilaria sp. 'Thailand II', or a quite divergent population of C. D. hongkongensis." @default.
- W2531077993 created "2016-10-21" @default.
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- W2531077993 date "2016-10-11" @default.
- W2531077993 modified "2023-10-14" @default.
- W2531077993 title "The Mitochondrial Genomes of the Zoonotic Canine Filarial Parasites Dirofilaria (Nochtiella) repens and Candidatus Dirofilaria (Nochtiella) Honkongensis Provide Evidence for Presence of Cryptic Species" @default.
- W2531077993 cites W102715436 @default.
- W2531077993 cites W131538023 @default.
- W2531077993 cites W147612560 @default.
- W2531077993 cites W1494995468 @default.
- W2531077993 cites W1500020214 @default.
- W2531077993 cites W1568473703 @default.
- W2531077993 cites W1859329567 @default.
- W2531077993 cites W1897644695 @default.
- W2531077993 cites W1944686013 @default.
- W2531077993 cites W1965591713 @default.
- W2531077993 cites W1967159460 @default.
- W2531077993 cites W1969042907 @default.
- W2531077993 cites W1976489354 @default.
- W2531077993 cites W1980882764 @default.
- W2531077993 cites W1983252070 @default.
- W2531077993 cites W1987201516 @default.
- W2531077993 cites W1992972802 @default.
- W2531077993 cites W1995563988 @default.
- W2531077993 cites W2003120160 @default.
- W2531077993 cites W2008831311 @default.
- W2531077993 cites W2009929072 @default.
- W2531077993 cites W2018009271 @default.
- W2531077993 cites W2025082543 @default.
- W2531077993 cites W2027482818 @default.
- W2531077993 cites W2028302194 @default.
- W2531077993 cites W2030058352 @default.
- W2531077993 cites W2033713984 @default.
- W2531077993 cites W2036960136 @default.
- W2531077993 cites W2037635593 @default.
- W2531077993 cites W2048227716 @default.
- W2531077993 cites W2058136068 @default.
- W2531077993 cites W2062560382 @default.
- W2531077993 cites W2075239457 @default.
- W2531077993 cites W2087076382 @default.
- W2531077993 cites W2091604112 @default.
- W2531077993 cites W2095082194 @default.
- W2531077993 cites W2097836098 @default.
- W2531077993 cites W2100929798 @default.
- W2531077993 cites W2101007196 @default.
- W2531077993 cites W2102344652 @default.
- W2531077993 cites W2103546861 @default.
- W2531077993 cites W2107627751 @default.
- W2531077993 cites W2111211467 @default.
- W2531077993 cites W2114750701 @default.
- W2531077993 cites W2119910220 @default.
- W2531077993 cites W2125867054 @default.
- W2531077993 cites W2128863631 @default.
- W2531077993 cites W2129762128 @default.
- W2531077993 cites W2130005298 @default.
- W2531077993 cites W2130198181 @default.
- W2531077993 cites W2131736110 @default.
- W2531077993 cites W2132926880 @default.
- W2531077993 cites W2138369959 @default.
- W2531077993 cites W2139134537 @default.
- W2531077993 cites W2141052558 @default.
- W2531077993 cites W2144362290 @default.
- W2531077993 cites W2144453642 @default.
- W2531077993 cites W2149429041 @default.
- W2531077993 cites W2152207030 @default.
- W2531077993 cites W2152758471 @default.
- W2531077993 cites W2154845780 @default.
- W2531077993 cites W2155645369 @default.
- W2531077993 cites W2156032139 @default.
- W2531077993 cites W2160378127 @default.
- W2531077993 cites W2163390948 @default.
- W2531077993 cites W2163798335 @default.
- W2531077993 cites W2164679538 @default.
- W2531077993 cites W2172200486 @default.
- W2531077993 cites W2173759594 @default.
- W2531077993 cites W2187052904 @default.
- W2531077993 cites W2187764400 @default.
- W2531077993 cites W2327139348 @default.
- W2531077993 cites W2359680669 @default.
- W2531077993 cites W2406934330 @default.
- W2531077993 cites W2423846244 @default.
- W2531077993 cites W2659935273 @default.
- W2531077993 cites W310004275 @default.
- W2531077993 cites W4250052351 @default.