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• W2531300178 abstract "Background. The roles of the sympathetic and parasympathetic systems in mediating the effect of electroacupuncture (EA) at ST37 on jejunal motility have yet to be demonstrated. Aim . We used rats and mice to investigate the effect and mechanism of action of EA at ST37 on jejunal motility. Methods. Jejunal motility was recorded by a balloon placed in the jejunum and connected to a biological signal collection system through a transducer. The effects of EA (3 mA) at ST37 were evaluated in Sprague-Dawley rats without drugs and with the administration of clenbuterol, propranolol, acetylcholine, and atropine. Further, the efficacy of EA at different intensities (1/2/4/6/8 mA) was measured in wild-type mice and<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:msup><mml:mrow><mml:msub><mml:mrow><mml:mi>β</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>1</mml:mn></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>β</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>2</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:mo>-</mml:mo><mml:mo>/</mml:mo><mml:mo>-</mml:mo></mml:mrow></mml:msup></mml:mrow></mml:math>mice and<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:msup><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant=normal>M</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>2</mml:mn></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi mathvariant=normal>M</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>3</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:mo>-</mml:mo><mml:mo>/</mml:mo><mml:mo>-</mml:mo></mml:mrow></mml:msup></mml:mrow></mml:math>mice. Results. In Sprague-Dawley rats, the excitatory effect of EA at ST37 on jejunal motility disappeared in the presence of the muscarinic receptor antagonist atropine. EA at ST37 was less effective in<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mrow><mml:msup><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant=normal>M</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>2</mml:mn></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi mathvariant=normal>M</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>3</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:mo>-</mml:mo><mml:mo>/</mml:mo><mml:mo>-</mml:mo></mml:mrow></mml:msup></mml:mrow></mml:math>mice than in wild-type mice. Furthermore, to a certain extent, there existed “intensity-response” relationship between jejunal motility and EA. Conclusions. EA at ST37 can enhance jejunal motility in rats and mice mainly via excitation of the parasympathetic pathway. There is an “intensity-response” relationship between EA and effect on jejunal motility." @default.
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• W2531300178 date "2016-01-01" @default.
• W2531300178 modified "2023-10-15" @default.
• W2531300178 title "Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice" @default.
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• W2531300178 doi "https://doi.org/10.1155/2016/3840230" @default.
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