FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2531489008> ?p ?o ?g. }

• W2531489008 endingPage "e28" @default.
• W2531489008 startingPage "e23" @default.
• W2531489008 abstract "Electronic cigarettes' (e-cigarettes) viability as a public health strategy to end smoking will likely be determined by their ability to mimic the pharmacokinetic profile of a cigarette while also exposing users to significantly lower levels of harmful/potentially harmful constituents (HPHCs). The present study examined the nicotine delivery profile of third- (G3) versus second-generation (G2) e-cigarette devices and their users' exposure to nicotine and select HPHCs compared with cigarette smokers.30 participants (10 smokers, 9 G2 and 11 G3 users) completed baseline questionnaires and provided exhaled carbon monoxide (eCO), saliva and urine samples. Following a 12-hour nicotine abstinence, G2 and G3 users completed a 2-hour vaping session (ie, 5 min, 10-puff bout followed by ad libitum puffing for 115 min). Blood samples, subjective effects, device characteristics and e-liquid consumption were assessed.Smokers, G2 and G3 users had similar baseline levels of cotinine, but smokers had 4 and 7 times higher levels of eCO (p<0.0001) and total 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (i.e., NNAL, p<0.01), respectively, than G2 or G3 users. Compared with G2s, G3 devices delivered significantly higher power to the atomiser, but G3 users vaped e-cigarette liquids with significantly lower nicotine concentrations. During the vaping session, G3 users achieved significantly higher plasma nicotine concentrations than G2 users following the first 10 puffs (17.5 vs 7.3 ng/mL, respectively) and at 25 and 40 min of ad libitum use. G3 users consumed significantly more e-liquid than G2 users. Vaping urges/withdrawal were reduced following 10 puffs, with no significant differences between device groups.Under normal use conditions, both G2 and G3 devices deliver cigarette-like amounts of nicotine, but G3 devices matched the amount and speed of nicotine delivery of a conventional cigarette. Compared with cigarettes, G2 and G3 e-cigarettes resulted in significantly lower levels of exposure to a potent lung carcinogen and cardiovascular toxicant. These findings have significant implications for understanding the addiction potential of these devices and their viability/suitability as aids to smoking cessation." @default.
• W2531489008 created "2016-10-21" @default.
• W2531489008 creator A5002415846 @default.
• W2531489008 creator A5008516772 @default.
• W2531489008 creator A5012909246 @default.
• W2531489008 creator A5013616302 @default.
• W2531489008 creator A5029782732 @default.
• W2531489008 creator A5034026004 @default.
• W2531489008 creator A5036498409 @default.
• W2531489008 creator A5050384161 @default.
• W2531489008 creator A5050590426 @default.
• W2531489008 creator A5073785288 @default.
• W2531489008 date "2016-10-11" @default.
• W2531489008 modified "2023-10-15" @default.
• W2531489008 title "Have combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette users" @default.
• W2531489008 cites W1742515314 @default.
• W2531489008 cites W1988060475 @default.
• W2531489008 cites W2009119212 @default.
• W2531489008 cites W2013319150 @default.
• W2531489008 cites W2038414756 @default.
• W2531489008 cites W2061961563 @default.
• W2531489008 cites W2081059621 @default.
• W2531489008 cites W2085892836 @default.
• W2531489008 cites W2089323330 @default.
• W2531489008 cites W2096533285 @default.
• W2531489008 cites W2106457238 @default.
• W2531489008 cites W2122581187 @default.
• W2531489008 cites W2125096607 @default.
• W2531489008 cites W2128456085 @default.
• W2531489008 cites W2135504811 @default.
• W2531489008 cites W2139740122 @default.
• W2531489008 cites W2144014211 @default.
• W2531489008 cites W2146048563 @default.
• W2531489008 cites W2155519999 @default.
• W2531489008 cites W2163581690 @default.
• W2531489008 cites W2168421628 @default.
• W2531489008 cites W2169404134 @default.
• W2531489008 cites W2172224821 @default.
• W2531489008 cites W2190146831 @default.
• W2531489008 cites W2193842232 @default.
• W2531489008 cites W2258296723 @default.
• W2531489008 cites W2325827278 @default.
• W2531489008 cites W2990789080 @default.
• W2531489008 doi "https://doi.org/10.1136/tobaccocontrol-2016-053041" @default.
• W2531489008 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5574194" @default.
• W2531489008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27729564" @default.
• W2531489008 hasPublicationYear "2016" @default.
• W2531489008 type Work @default.
• W2531489008 sameAs 2531489008 @default.
• W2531489008 citedByCount "214" @default.
• W2531489008 countsByYear W25314890082016 @default.
• W2531489008 countsByYear W25314890082017 @default.
• W2531489008 countsByYear W25314890082018 @default.
• W2531489008 countsByYear W25314890082019 @default.
• W2531489008 countsByYear W25314890082020 @default.
• W2531489008 countsByYear W25314890082021 @default.
• W2531489008 countsByYear W25314890082022 @default.
• W2531489008 countsByYear W25314890082023 @default.
• W2531489008 crossrefType "journal-article" @default.
• W2531489008 hasAuthorship W2531489008A5002415846 @default.
• W2531489008 hasAuthorship W2531489008A5008516772 @default.
• W2531489008 hasAuthorship W2531489008A5012909246 @default.
• W2531489008 hasAuthorship W2531489008A5013616302 @default.
• W2531489008 hasAuthorship W2531489008A5029782732 @default.
• W2531489008 hasAuthorship W2531489008A5034026004 @default.
• W2531489008 hasAuthorship W2531489008A5036498409 @default.
• W2531489008 hasAuthorship W2531489008A5050384161 @default.
• W2531489008 hasAuthorship W2531489008A5050590426 @default.
• W2531489008 hasAuthorship W2531489008A5073785288 @default.
• W2531489008 hasBestOaLocation W25314890081 @default.
• W2531489008 hasConcept C118552586 @default.
• W2531489008 hasConcept C126322002 @default.
• W2531489008 hasConcept C142724271 @default.
• W2531489008 hasConcept C185592680 @default.
• W2531489008 hasConcept C2776319443 @default.
• W2531489008 hasConcept C2776970978 @default.
• W2531489008 hasConcept C2777843972 @default.
• W2531489008 hasConcept C2779547902 @default.
• W2531489008 hasConcept C2780026642 @default.
• W2531489008 hasConcept C2780687700 @default.
• W2531489008 hasConcept C71924100 @default.
• W2531489008 hasConceptScore W2531489008C118552586 @default.
• W2531489008 hasConceptScore W2531489008C126322002 @default.
• W2531489008 hasConceptScore W2531489008C142724271 @default.
• W2531489008 hasConceptScore W2531489008C185592680 @default.
• W2531489008 hasConceptScore W2531489008C2776319443 @default.
• W2531489008 hasConceptScore W2531489008C2776970978 @default.
• W2531489008 hasConceptScore W2531489008C2777843972 @default.
• W2531489008 hasConceptScore W2531489008C2779547902 @default.
• W2531489008 hasConceptScore W2531489008C2780026642 @default.
• W2531489008 hasConceptScore W2531489008C2780687700 @default.
• W2531489008 hasConceptScore W2531489008C71924100 @default.
• W2531489008 hasIssue "e1" @default.
• W2531489008 hasLocation W25314890081 @default.
• W2531489008 hasLocation W25314890082 @default.
• W2531489008 hasLocation W25314890083 @default.
• W2531489008 hasLocation W25314890084 @default.
• W2531489008 hasOpenAccess W2531489008 @default.

• next