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- W2531552252 abstract "Aim: To characterize inter- and intra-strain variability of variable-number tandem repeats (VNTRs) in Mycoplasma pneumoniae to determine the optimal multilocus VNTR analysis scheme for improved strain typing. Methods: Whole genome assemblies and next-generation sequencing data from diverse M. pneumoniae isolates were used to characterize VNTRs and their variability, and to compare the strain discriminability of new VNTR and existing markers. Results: We identified 13 VNTRs including five reported previously. These VNTRs displayed different levels of inter- and intra-strain copy number variations. All new markers showed similar or higher discriminability compared with existing VNTR markers and the P1 typing system. Conclusion: Our study provides novel insights into VNTR variations and potential new multilocus VNTR analysis schemes for improved genotyping of M. pneumoniae." @default.
- W2531552252 created "2016-10-21" @default.
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- W2531552252 date "2017-02-01" @default.
- W2531552252 modified "2023-09-27" @default.
- W2531552252 title "Inter- and intra-strain variability of tandem repeats in Mycoplasma pneumoniae based on next-generation sequencing data" @default.
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- W2531552252 doi "https://doi.org/10.2217/fmb-2016-0111" @default.
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