Matches in SemOpenAlex for { <https://semopenalex.org/work/W2531738154> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2531738154 endingPage "248" @default.
- W2531738154 startingPage "238" @default.
- W2531738154 abstract "The effect of moderate craniocerebral hypothermia (CCH) (32°C) on total proteinase activity (TPA), the activity of non-trypsin-like proteinases (NTLP) and their inhibitors (a-1-proteinase inhibitor (a-1-PI) and a-2-macroglobulin (a-2-MG) in the tissue samples of CNS (brain cortex, hypothalamus, cerebellum), peripheral organs (heart, lungs, liver, kidneys) and serum blood in rats was studied. In all the samples studied a sharp increase in the TPA (by one to two orders) and the NTLP activity (in several times) under CCH were observed. At the same time, against the background of constant a-1-PI activity the dynamics of the a-2-MG activity were multidirectional and tissue-specific: it was increased in blood serum, hypothalamus and heart, decreased in kidneys and cerebellum, and did not change in other tissues. Twenty four hours after the CCH application, the TPA remained at the same high activity level, the NTLP activity returned to baseline levels in the most samples, the activity of a-1-PI decreased only in the brain cortex and hypothalamus; the a‑2‑MG activity decreased in hypothalamus, cerebellum and kidneys, increased in liver and heart and returned to the baseline levels in other samples. The sharp proteinases activation, shift of the dynamic balance between enzymes and their inhibitors under CCH and in the recovery phase may indicate crucial changes in the orgamism systems aimed at implementation of protective and therapeutic mechanisms. Probl. Cryobiol. Cryomed. 2016; 26(3): 238–248" @default.
- W2531738154 created "2016-10-21" @default.
- W2531738154 creator A5042321278 @default.
- W2531738154 creator A5048660208 @default.
- W2531738154 creator A5069198191 @default.
- W2531738154 creator A5080263954 @default.
- W2531738154 date "2016-09-26" @default.
- W2531738154 modified "2023-09-24" @default.
- W2531738154 title "Craniocerebral Hypothermia Stimulates Reactions of Limited Proteolysis in Rat Tissues" @default.
- W2531738154 cites W1967043664 @default.
- W2531738154 cites W1979916433 @default.
- W2531738154 cites W1981234524 @default.
- W2531738154 cites W1995941626 @default.
- W2531738154 cites W2008450997 @default.
- W2531738154 cites W2034157973 @default.
- W2531738154 cites W2043931150 @default.
- W2531738154 cites W2077212354 @default.
- W2531738154 cites W2103657305 @default.
- W2531738154 cites W2116422254 @default.
- W2531738154 cites W2127831042 @default.
- W2531738154 cites W2414232855 @default.
- W2531738154 cites W3188267669 @default.
- W2531738154 doi "https://doi.org/10.15407/cryo26.03.238" @default.
- W2531738154 hasPublicationYear "2016" @default.
- W2531738154 type Work @default.
- W2531738154 sameAs 2531738154 @default.
- W2531738154 citedByCount "3" @default.
- W2531738154 countsByYear W25317381542017 @default.
- W2531738154 countsByYear W25317381542022 @default.
- W2531738154 countsByYear W25317381542023 @default.
- W2531738154 crossrefType "journal-article" @default.
- W2531738154 hasAuthorship W2531738154A5042321278 @default.
- W2531738154 hasAuthorship W2531738154A5048660208 @default.
- W2531738154 hasAuthorship W2531738154A5069198191 @default.
- W2531738154 hasAuthorship W2531738154A5080263954 @default.
- W2531738154 hasBestOaLocation W25317381541 @default.
- W2531738154 hasConcept C126322002 @default.
- W2531738154 hasConcept C134018914 @default.
- W2531738154 hasConcept C169760540 @default.
- W2531738154 hasConcept C181199279 @default.
- W2531738154 hasConcept C185592680 @default.
- W2531738154 hasConcept C198684833 @default.
- W2531738154 hasConcept C2777003273 @default.
- W2531738154 hasConcept C2777348757 @default.
- W2531738154 hasConcept C2777390192 @default.
- W2531738154 hasConcept C2779652256 @default.
- W2531738154 hasConcept C2780340462 @default.
- W2531738154 hasConcept C2781307694 @default.
- W2531738154 hasConcept C55493867 @default.
- W2531738154 hasConcept C71924100 @default.
- W2531738154 hasConcept C86803240 @default.
- W2531738154 hasConceptScore W2531738154C126322002 @default.
- W2531738154 hasConceptScore W2531738154C134018914 @default.
- W2531738154 hasConceptScore W2531738154C169760540 @default.
- W2531738154 hasConceptScore W2531738154C181199279 @default.
- W2531738154 hasConceptScore W2531738154C185592680 @default.
- W2531738154 hasConceptScore W2531738154C198684833 @default.
- W2531738154 hasConceptScore W2531738154C2777003273 @default.
- W2531738154 hasConceptScore W2531738154C2777348757 @default.
- W2531738154 hasConceptScore W2531738154C2777390192 @default.
- W2531738154 hasConceptScore W2531738154C2779652256 @default.
- W2531738154 hasConceptScore W2531738154C2780340462 @default.
- W2531738154 hasConceptScore W2531738154C2781307694 @default.
- W2531738154 hasConceptScore W2531738154C55493867 @default.
- W2531738154 hasConceptScore W2531738154C71924100 @default.
- W2531738154 hasConceptScore W2531738154C86803240 @default.
- W2531738154 hasIssue "3" @default.
- W2531738154 hasLocation W25317381541 @default.
- W2531738154 hasOpenAccess W2531738154 @default.
- W2531738154 hasPrimaryLocation W25317381541 @default.
- W2531738154 hasRelatedWork W2012116480 @default.
- W2531738154 hasRelatedWork W2051488242 @default.
- W2531738154 hasRelatedWork W2056116732 @default.
- W2531738154 hasRelatedWork W2066173879 @default.
- W2531738154 hasRelatedWork W2070793461 @default.
- W2531738154 hasRelatedWork W2074115578 @default.
- W2531738154 hasRelatedWork W2084435836 @default.
- W2531738154 hasRelatedWork W2110497742 @default.
- W2531738154 hasRelatedWork W2471757216 @default.
- W2531738154 hasRelatedWork W2773858965 @default.
- W2531738154 hasVolume "26" @default.
- W2531738154 isParatext "false" @default.
- W2531738154 isRetracted "false" @default.
- W2531738154 magId "2531738154" @default.
- W2531738154 workType "article" @default.