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• W2531931036 endingPage "179" @default.
• W2531931036 startingPage "169" @default.
• W2531931036 abstract "Background and purposeVolume delineation is a well-recognised potential source of error in radiotherapy. Whilst it is important to quantify the degree of interobserver variability (IOV) in volume delineation, the resulting impact on dosimetry and clinical outcomes is a more relevant endpoint. We performed a literature review of studies evaluating IOV in target volume and organ-at-risk (OAR) delineation in order to analyse these with respect to the metrics used, reporting of dosimetric consequences, and use of statistical tests.Methods and materialsMedline and Pubmed databases were queried for relevant articles using keywords. We included studies published in English between 2000 and 2014 with more than two observers.Results119 studies were identified covering all major tumour sites. CTV (n = 47) and GTV (n = 38) were most commonly contoured. Median number of participants and data sets were 7 (3–50) and 9 (1–132) respectively. There was considerable heterogeneity in the use of metrics and methods of analysis. Statistical analysis of results was reported in 68% (n = 81) and dosimetric consequences in 21% (n = 25) of studies.ConclusionThere is a lack of consistency in conducting and reporting analyses from IOV studies. We suggest a framework to use for future studies evaluating IOV." @default.
• W2531931036 created "2016-10-21" @default.
• W2531931036 creator A5006934380 @default.
• W2531931036 creator A5014481486 @default.
• W2531931036 creator A5052648825 @default.
• W2531931036 creator A5061844500 @default.
• W2531931036 date "2016-11-01" @default.
• W2531931036 modified "2023-10-18" @default.
• W2531931036 title "Uncertainties in volume delineation in radiation oncology: A systematic review and recommendations for future studies" @default.
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