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- W2532004265 endingPage "kew340" @default.
- W2532004265 startingPage "kew340" @default.
- W2532004265 abstract "SLE is a chronic autoimmune disease involving multiple systems. Patients with SLE are highly susceptible to infections due to the combined effects of their immunosuppressive therapy and the abnormalities of the immune system that the disease itself causes, which can increase mortality in these patients. The differentiation of SLE activity and infection in a febrile patient with SLE is extremely difficult. Activity indexes are useful to identify patients with lupus flares but some clinical and biological abnormalities may, however, make it difficult to differentiate flares from infection. Several biological markers are now recognized as potential tools to establish the difference between SLE activity and infection, including CRP and procalcitonin. It is possible, however, that the use of only one biomarker is not sufficient to confirm or discard infection. This means that new scores, which include different biomarkers, might represent a better solution for differentiating these two clinical pictures. This review article describes several markers that are currently used, or have the potential, to differentiate infection from SLE flares." @default.
- W2532004265 created "2016-10-28" @default.
- W2532004265 creator A5016565131 @default.
- W2532004265 creator A5025310479 @default.
- W2532004265 creator A5029379669 @default.
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- W2532004265 creator A5046899239 @default.
- W2532004265 creator A5060298804 @default.
- W2532004265 creator A5064018959 @default.
- W2532004265 date "2016-10-15" @default.
- W2532004265 modified "2023-10-15" @default.
- W2532004265 title "Distinguishing infections<i>vs</i>flares in patients with systemic lupus erythematosus: Table 1" @default.
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