Matches in SemOpenAlex for { <https://semopenalex.org/work/W2533006040> ?p ?o ?g. }
- W2533006040 endingPage "214" @default.
- W2533006040 startingPage "204" @default.
- W2533006040 abstract "Rational drug design is undoubtedly an extremely important objective for chemists and biologists. As a step in this direction, quantitative understanding of physical chemistry underlying partitioning of drugs in drug delivery vehicles such as micelles provides guidelines to meet such an objective. Interactions of tryptophan (chosen as a model drug) and diclofenac sodium (nonsteroidal anti-inflammatory drug) have been studied with the micelles and monomers of cationic surfactant hexadecyoltrimethylammonium bromide (HTAB), non-ionic surfactant triton X-100 (TX-100), and their mixture. This has been addressed in terms of changes in physicochemical properties such as standard molar enthalpy, entropy and Gibbs free energy of partitioning in combination with pyrene fluorescence emission and dynamic light scattering measurements. The mechanism of partitioning of the drugs in individual micelles, micellar mixture, and interaction behavior with the monomers has been discussed. The energetics of interaction of partitioning, correlated with the functional groups on a wide range of drugs can be very important in deriving guidelines for target oriented synthesis. The effect of drugs on micellization properties of HTAB, TX-100 and their mixture has also been addressed." @default.
- W2533006040 created "2016-10-28" @default.
- W2533006040 creator A5056917493 @default.
- W2533006040 creator A5074269390 @default.
- W2533006040 date "2017-01-01" @default.
- W2533006040 modified "2023-09-25" @default.
- W2533006040 title "Partitioning of drugs in micelles and effect on micellization: Physicochemical insights with tryptophan and diclofenac sodium" @default.
- W2533006040 cites W1245318737 @default.
- W2533006040 cites W1528446300 @default.
- W2533006040 cites W1541421229 @default.
- W2533006040 cites W1982254724 @default.
- W2533006040 cites W1985052076 @default.
- W2533006040 cites W1985733321 @default.
- W2533006040 cites W1993053769 @default.
- W2533006040 cites W2008568218 @default.
- W2533006040 cites W2017487232 @default.
- W2533006040 cites W2023330601 @default.
- W2533006040 cites W2025561938 @default.
- W2533006040 cites W2032295890 @default.
- W2533006040 cites W2035044547 @default.
- W2533006040 cites W2043567599 @default.
- W2533006040 cites W2050721739 @default.
- W2533006040 cites W2053537956 @default.
- W2533006040 cites W2056691948 @default.
- W2533006040 cites W2058366525 @default.
- W2533006040 cites W2060751536 @default.
- W2533006040 cites W2073925912 @default.
- W2533006040 cites W2075205958 @default.
- W2533006040 cites W2076663214 @default.
- W2533006040 cites W2076695408 @default.
- W2533006040 cites W2078439031 @default.
- W2533006040 cites W2079419473 @default.
- W2533006040 cites W2081960276 @default.
- W2533006040 cites W2087985547 @default.
- W2533006040 cites W2091060393 @default.
- W2533006040 cites W2109498048 @default.
- W2533006040 cites W2124591070 @default.
- W2533006040 cites W2131241717 @default.
- W2533006040 cites W2141379475 @default.
- W2533006040 cites W2416144252 @default.
- W2533006040 cites W3103982839 @default.
- W2533006040 doi "https://doi.org/10.1016/j.colsurfa.2016.10.044" @default.
- W2533006040 hasPublicationYear "2017" @default.
- W2533006040 type Work @default.
- W2533006040 sameAs 2533006040 @default.
- W2533006040 citedByCount "18" @default.
- W2533006040 countsByYear W25330060402017 @default.
- W2533006040 countsByYear W25330060402018 @default.
- W2533006040 countsByYear W25330060402019 @default.
- W2533006040 countsByYear W25330060402020 @default.
- W2533006040 countsByYear W25330060402021 @default.
- W2533006040 countsByYear W25330060402022 @default.
- W2533006040 countsByYear W25330060402023 @default.
- W2533006040 crossrefType "journal-article" @default.
- W2533006040 hasAuthorship W2533006040A5056917493 @default.
- W2533006040 hasAuthorship W2533006040A5074269390 @default.
- W2533006040 hasConcept C11268172 @default.
- W2533006040 hasConcept C118552586 @default.
- W2533006040 hasConcept C121332964 @default.
- W2533006040 hasConcept C146477669 @default.
- W2533006040 hasConcept C15744967 @default.
- W2533006040 hasConcept C178790620 @default.
- W2533006040 hasConcept C181389837 @default.
- W2533006040 hasConcept C183882617 @default.
- W2533006040 hasConcept C184651966 @default.
- W2533006040 hasConcept C185592680 @default.
- W2533006040 hasConcept C2776300020 @default.
- W2533006040 hasConcept C2778951431 @default.
- W2533006040 hasConcept C2779820397 @default.
- W2533006040 hasConcept C2780035454 @default.
- W2533006040 hasConcept C2908765736 @default.
- W2533006040 hasConcept C43617362 @default.
- W2533006040 hasConcept C55493867 @default.
- W2533006040 hasConcept C58226133 @default.
- W2533006040 hasConcept C60644358 @default.
- W2533006040 hasConcept C86803240 @default.
- W2533006040 hasConcept C97355855 @default.
- W2533006040 hasConceptScore W2533006040C11268172 @default.
- W2533006040 hasConceptScore W2533006040C118552586 @default.
- W2533006040 hasConceptScore W2533006040C121332964 @default.
- W2533006040 hasConceptScore W2533006040C146477669 @default.
- W2533006040 hasConceptScore W2533006040C15744967 @default.
- W2533006040 hasConceptScore W2533006040C178790620 @default.
- W2533006040 hasConceptScore W2533006040C181389837 @default.
- W2533006040 hasConceptScore W2533006040C183882617 @default.
- W2533006040 hasConceptScore W2533006040C184651966 @default.
- W2533006040 hasConceptScore W2533006040C185592680 @default.
- W2533006040 hasConceptScore W2533006040C2776300020 @default.
- W2533006040 hasConceptScore W2533006040C2778951431 @default.
- W2533006040 hasConceptScore W2533006040C2779820397 @default.
- W2533006040 hasConceptScore W2533006040C2780035454 @default.
- W2533006040 hasConceptScore W2533006040C2908765736 @default.
- W2533006040 hasConceptScore W2533006040C43617362 @default.
- W2533006040 hasConceptScore W2533006040C55493867 @default.
- W2533006040 hasConceptScore W2533006040C58226133 @default.
- W2533006040 hasConceptScore W2533006040C60644358 @default.
- W2533006040 hasConceptScore W2533006040C86803240 @default.
- W2533006040 hasConceptScore W2533006040C97355855 @default.