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- W2533292636 abstract "With the ultra-high sensitive technology, so-called immunomagnetic immunoassay, the tau protein in human plasma can be precisely detected. Sixty-two healthy subjects from 50 to 81 years old living in Taiwan are recruited. In addition, twenty-four patients with mild cognition impairment (MCI) due to Alzheimer’s disease (AD) and twenty-nine patients early-stage AD are enrolled for the assay of plasma tau protein. The healthy subjects show the lowest plasma tau-protein concentrations, while the AD group shows the highest concentrations for plasma tau protein. Through a careful inspection for the plasma tau-protein concentrations of healthy subjects, the plasma tau-protein concentration slightly increases with aging. Meanwhile, the atrophy in hippocampal volume of the healthy subjects was found as the age becomes higher. These results reveal the fact that the atrophy in hippocampus naturally occurs and the elevation in plasma tau protein is normally found due to aging." @default.
- W2533292636 created "2016-10-28" @default.
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- W2533292636 date "2016-07-01" @default.
- W2533292636 modified "2023-09-27" @default.
- W2533292636 title "P2-132: Elevation in Plasma TAU Protein Due to Normal Aging" @default.
- W2533292636 doi "https://doi.org/10.1016/j.jalz.2016.06.1502" @default.
- W2533292636 hasPublicationYear "2016" @default.
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