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- W253413980 abstract "SUMMARY: Effects of dietary myo-inositol deficiency were examined during prenatal and postnatal development and during lactation in the rat. The supplemented diet contained 0.5% (w/w) myo-inositol at the expense of sucrose. Both diets contained 25% casein, adequate amounts of all known vitamins, choline and essential fatty acids and 0.5% (w/w) phthalylsulfathiazole to depress myo-inositol contribution to the diet by microorganisms. During lactation, the myo-inositol-deprived dams developed severe fatty livers. After only 4 days of lactation, cholesterol esters and triglyceride levels were significantly elevated in the liver, whereas phospholipid levels were significantly depressed in the livers of myo-inositol-deficient dams compared with those fed myo-inositol-supplemented diets. By electron microscopy, numerous large intracellular lipid droplets were detected in the livers of dams deprived of myo-inositol after 14 days of lactation." @default.
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- W253413980 date "1978-01-01" @default.
- W253413980 modified "2023-10-14" @default.
- W253413980 title "REQUIREMENT FOR DIETARY myo-INOSITOL IN THE LACTATING RAT" @default.
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- W253413980 doi "https://doi.org/10.1016/b978-0-12-741750-9.50039-2" @default.
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