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- W2534460400 abstract "Linear epidermal nevus (LEN) is an hamartomatous lesion of the skin caused by a proliferation of embryonic ectodermal cells distributed in a linear pattern following Blaschkos lines. Oral involvement of LEN is rare, with only few cases reported to date in the English literature. Oral LEN usually appears as verrruco-papillary lesion present at birth or during childhood. Most cases of oral LENs are associated with cutaneous lesions. Oral LENs without skin involvement are extremely rare. Approximately 6 cases of LEN with exclusive oral involvement have been reported since the first documented cases by Brown and Gorlin in 1960. We report a case of LEN confined to the oral mucosa. A 5-year-old boy was referred by a general dentist to the oral pathology clinic for evaluation of a pink papillary lesion located in the midline of the hard and soft palate extending to the uvula. The lesion presented a characteristic linear pattern of distribution. No skin lesions were discovered during the clinical examination. An incisional biopsy was taken. Microscopic examination revealed an epithelial lesion with papillary projections surfaced by a hyperparakeratinized stratified squamous epithelium with acanthosis and elongated rete ridges. A mild chronic inflammatory infiltrate was present in the underlying lamina propria. No further treatment was performed. After a 1-month follow-up period, no significant changes were observed in the lesion." @default.
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- W2534460400 date "2016-11-01" @default.
- W2534460400 modified "2023-09-23" @default.
- W2534460400 title "ORAL LINEAR EPIDERMAL NEVUS: A CASE REPORT AND REVIEW OF THE LITERATURE" @default.
- W2534460400 doi "https://doi.org/10.1016/j.oooo.2016.06.053" @default.
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