Matches in SemOpenAlex for { <https://semopenalex.org/work/W2534702194> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2534702194 abstract "The development and use of endosseous implants in dentistry have increased worldwide since the introduction of the concept of osseointegration. This concept of a direct bone-to-metal interface, according to Branemark, consists of a highly differentiated tissue making a direct structural and functional connection between ordered living bone and the surface of an implant. Much of the research supporting this concept was based on in vivo animal studies and clinical results from human patients. In vitro models are increasingly being used to examine the short-term behaviour and function of connective tissue cells on implant surfaces. The first section of this thesis presents an examination of the dynamic behaviour of fibroblast cells cultured in vitro, using time-laspe video micrography, to evaluate initial attachment and spreading. It is acknowledged that in vitro culturing of isolated cells on the biomaterials may not represent all the characteristics of tissue responses around dental implants in vivo since the structural organization of connective tissue is lost in these systems. The main aim of the work presented in this thesis was to develop a new organ culture model for studying bone-biomaterial interactions. This model is based on grafting bone explants onto the chorioallantoic membrane (CAM) of chick eggs. The model was characterised to provide a test bed for the assessment of early bone-biomaterial interactions. The stages of development of the early bone-implant interface were studied using commercially pure titanium and a glass ceramic material, Apoceram. Light microscopy, histochemical, ultrastructural and immunocytochemical examinations were carried out. The feasibility of using the model for studying the effects of basic fibroblast growth factor on bone healing around the implants was assessed and the role of the CAM graft model as a bridge between in vitro and in vivo methods of studying bone-implant interactions examined." @default.
- W2534702194 created "2016-10-28" @default.
- W2534702194 creator A5001530370 @default.
- W2534702194 date "1998-01-01" @default.
- W2534702194 modified "2023-09-27" @default.
- W2534702194 title "Cellular and tissue responses to implant materials : development of a novel organ culture model." @default.
- W2534702194 hasPublicationYear "1998" @default.
- W2534702194 type Work @default.
- W2534702194 sameAs 2534702194 @default.
- W2534702194 citedByCount "0" @default.
- W2534702194 crossrefType "dissertation" @default.
- W2534702194 hasAuthorship W2534702194A5001530370 @default.
- W2534702194 hasConcept C101414908 @default.
- W2534702194 hasConcept C125473707 @default.
- W2534702194 hasConcept C136229726 @default.
- W2534702194 hasConcept C141071460 @default.
- W2534702194 hasConcept C142724271 @default.
- W2534702194 hasConcept C192562407 @default.
- W2534702194 hasConcept C199343813 @default.
- W2534702194 hasConcept C2778414984 @default.
- W2534702194 hasConcept C2781411149 @default.
- W2534702194 hasConcept C518705261 @default.
- W2534702194 hasConcept C64837602 @default.
- W2534702194 hasConcept C71924100 @default.
- W2534702194 hasConcept C74864618 @default.
- W2534702194 hasConceptScore W2534702194C101414908 @default.
- W2534702194 hasConceptScore W2534702194C125473707 @default.
- W2534702194 hasConceptScore W2534702194C136229726 @default.
- W2534702194 hasConceptScore W2534702194C141071460 @default.
- W2534702194 hasConceptScore W2534702194C142724271 @default.
- W2534702194 hasConceptScore W2534702194C192562407 @default.
- W2534702194 hasConceptScore W2534702194C199343813 @default.
- W2534702194 hasConceptScore W2534702194C2778414984 @default.
- W2534702194 hasConceptScore W2534702194C2781411149 @default.
- W2534702194 hasConceptScore W2534702194C518705261 @default.
- W2534702194 hasConceptScore W2534702194C64837602 @default.
- W2534702194 hasConceptScore W2534702194C71924100 @default.
- W2534702194 hasConceptScore W2534702194C74864618 @default.
- W2534702194 hasLocation W25347021941 @default.
- W2534702194 hasOpenAccess W2534702194 @default.
- W2534702194 hasPrimaryLocation W25347021941 @default.
- W2534702194 hasRelatedWork W1802103619 @default.
- W2534702194 hasRelatedWork W1993097709 @default.
- W2534702194 hasRelatedWork W2072490913 @default.
- W2534702194 hasRelatedWork W2080408646 @default.
- W2534702194 hasRelatedWork W2112110053 @default.
- W2534702194 hasRelatedWork W2126158167 @default.
- W2534702194 hasRelatedWork W2132047049 @default.
- W2534702194 hasRelatedWork W2137233354 @default.
- W2534702194 hasRelatedWork W2202991422 @default.
- W2534702194 hasRelatedWork W2322191166 @default.
- W2534702194 hasRelatedWork W2395842974 @default.
- W2534702194 hasRelatedWork W2396048073 @default.
- W2534702194 hasRelatedWork W2396382687 @default.
- W2534702194 hasRelatedWork W2574145078 @default.
- W2534702194 hasRelatedWork W2739950869 @default.
- W2534702194 hasRelatedWork W2792433136 @default.
- W2534702194 hasRelatedWork W2799892244 @default.
- W2534702194 hasRelatedWork W2801156816 @default.
- W2534702194 hasRelatedWork W3133534838 @default.
- W2534702194 hasRelatedWork W1525347618 @default.
- W2534702194 isParatext "false" @default.
- W2534702194 isRetracted "false" @default.
- W2534702194 magId "2534702194" @default.
- W2534702194 workType "dissertation" @default.