FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2535664532> ?p ?o ?g. }

• W2535664532 endingPage "19" @default.
• W2535664532 startingPage "5" @default.
• W2535664532 abstract "A bidirectional crosstalk between nociceptor sensory neurons and immune cells actively regulates pain and inflammation. Immune cells release lipids, cytokines, and growth factors that have a key role in sensitizing nociceptor sensory neurons by acting in peripheral tissues and the spinal cord to produce neuronal plasticity and chronic pain. Nociceptor neurons release neuropeptides that drive changes in the vasculature, lymphatics, and polarization of innate and adaptive immune cell function. Nociceptor neurons modulate host defenses against bacterial and fungal pathogens, and, in some cases, neural activity benefits the host, while in others, it benefits the pathogen. Interactions between nociceptor neurons and immune cells contribute to pathology in chronic inflammatory diseases, including rheumatoid arthritis, psoriasis, asthmatic lung disease, and colitis. Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly clear that active crosstalk occurs between nociceptor neurons and the immune system to regulate pain, host defense, and inflammatory diseases. Immune cells at peripheral nerve terminals and within the spinal cord release mediators that modulate mechanical and thermal sensitivity. In turn, nociceptor neurons release neuropeptides and neurotransmitters from nerve terminals that regulate vascular, innate, and adaptive immune cell responses. Therefore, the dialog between nociceptor neurons and the immune system is a fundamental aspect of inflammation, both acute and chronic. A better understanding of these interactions could produce approaches to treat chronic pain and inflammatory diseases. Nociceptor sensory neurons protect organisms from danger by eliciting pain and driving avoidance. Pain also accompanies many types of inflammation and injury. It is increasingly clear that active crosstalk occurs between nociceptor neurons and the immune system to regulate pain, host defense, and inflammatory diseases. Immune cells at peripheral nerve terminals and within the spinal cord release mediators that modulate mechanical and thermal sensitivity. In turn, nociceptor neurons release neuropeptides and neurotransmitters from nerve terminals that regulate vascular, innate, and adaptive immune cell responses. Therefore, the dialog between nociceptor neurons and the immune system is a fundamental aspect of inflammation, both acute and chronic. A better understanding of these interactions could produce approaches to treat chronic pain and inflammatory diseases." @default.
• W2535664532 created "2016-10-28" @default.
• W2535664532 creator A5026822066 @default.
• W2535664532 creator A5035877999 @default.
• W2535664532 creator A5078024039 @default.
• W2535664532 date "2017-01-01" @default.
• W2535664532 modified "2023-10-18" @default.
• W2535664532 title "Nociceptor Sensory Neuron–Immune Interactions in Pain and Inflammation" @default.
• W2535664532 cites W1513929611 @default.
• W2535664532 cites W1536951294 @default.
• W2535664532 cites W1590732890 @default.
• W2535664532 cites W1620827315 @default.
• W2535664532 cites W1623465125 @default.
• W2535664532 cites W1774995177 @default.
• W2535664532 cites W1929453196 @default.
• W2535664532 cites W1963857381 @default.
• W2535664532 cites W1966969515 @default.
• W2535664532 cites W1968008199 @default.
• W2535664532 cites W1972864851 @default.
• W2535664532 cites W1973256550 @default.
• W2535664532 cites W1973261188 @default.
• W2535664532 cites W1979137100 @default.
• W2535664532 cites W1979246434 @default.
• W2535664532 cites W1982025383 @default.
• W2535664532 cites W1982381655 @default.
• W2535664532 cites W1984632338 @default.
• W2535664532 cites W1988325008 @default.
• W2535664532 cites W1991488724 @default.
• W2535664532 cites W1993285878 @default.
• W2535664532 cites W1995374814 @default.
• W2535664532 cites W1998495773 @default.
• W2535664532 cites W2000574545 @default.
• W2535664532 cites W2001650386 @default.
• W2535664532 cites W2001699192 @default.
• W2535664532 cites W2006767554 @default.
• W2535664532 cites W2007755013 @default.
• W2535664532 cites W2008248479 @default.
• W2535664532 cites W2009686533 @default.
• W2535664532 cites W2010290939 @default.
• W2535664532 cites W2013738868 @default.
• W2535664532 cites W2013876494 @default.
• W2535664532 cites W2014801387 @default.
• W2535664532 cites W2015386261 @default.
• W2535664532 cites W2016237453 @default.
• W2535664532 cites W2016558548 @default.
• W2535664532 cites W2016854123 @default.
• W2535664532 cites W2022168094 @default.
• W2535664532 cites W2024434614 @default.
• W2535664532 cites W2025897361 @default.
• W2535664532 cites W2030621034 @default.
• W2535664532 cites W2033106089 @default.
• W2535664532 cites W2034208991 @default.
• W2535664532 cites W2040393757 @default.
• W2535664532 cites W2040489572 @default.
• W2535664532 cites W2042317973 @default.
• W2535664532 cites W2047751078 @default.
• W2535664532 cites W2050432921 @default.
• W2535664532 cites W2050792388 @default.
• W2535664532 cites W2055435244 @default.
• W2535664532 cites W2062993520 @default.
• W2535664532 cites W2065432788 @default.
• W2535664532 cites W2067087807 @default.
• W2535664532 cites W2067532382 @default.
• W2535664532 cites W2067840455 @default.
• W2535664532 cites W2067954401 @default.
• W2535664532 cites W2070412945 @default.
• W2535664532 cites W2071425405 @default.
• W2535664532 cites W2071602597 @default.
• W2535664532 cites W2073672889 @default.
• W2535664532 cites W2075715972 @default.
• W2535664532 cites W2080991292 @default.
• W2535664532 cites W2082709992 @default.
• W2535664532 cites W2083074276 @default.
• W2535664532 cites W2084942699 @default.
• W2535664532 cites W2087214422 @default.
• W2535664532 cites W2088625735 @default.
• W2535664532 cites W2090609282 @default.
• W2535664532 cites W2090722957 @default.
• W2535664532 cites W2092211307 @default.
• W2535664532 cites W2093441252 @default.
• W2535664532 cites W2099991752 @default.
• W2535664532 cites W2103447688 @default.
• W2535664532 cites W2109644936 @default.
• W2535664532 cites W2115158780 @default.
• W2535664532 cites W2116534834 @default.
• W2535664532 cites W2119362958 @default.
• W2535664532 cites W2122025387 @default.
• W2535664532 cites W2124503501 @default.
• W2535664532 cites W2124879125 @default.
• W2535664532 cites W2126283897 @default.
• W2535664532 cites W2127744906 @default.
• W2535664532 cites W2128659492 @default.
• W2535664532 cites W2128865950 @default.
• W2535664532 cites W2130593605 @default.
• W2535664532 cites W2131273766 @default.
• W2535664532 cites W2134557769 @default.
• W2535664532 cites W2137445147 @default.
• W2535664532 cites W2141362791 @default.

• next