Matches in SemOpenAlex for { <https://semopenalex.org/work/W2535873244> ?p ?o ?g. }
- W2535873244 endingPage "5666" @default.
- W2535873244 startingPage "5656" @default.
- W2535873244 abstract "Recent experiments suggest that an amino acid sequence encodes not only the native fold of a protein but also other forms that are essential for its function or are important during folding or association. These various forms populate a multifunnel folding and association landscape where mutations, changes in environment, or interaction with other molecules switch between the encoded folds. We introduce replica exchange with tunneling as a way to efficiently simulate switching between distinct folds of proteins and protein aggregates. The correctness and efficiency of our approach are demonstrated in a series of simulations covering a wide range of proteins, from a small 11-residue large designed peptide to two 56-residue large mutants of the A and B domains of protein G." @default.
- W2535873244 created "2016-10-28" @default.
- W2535873244 creator A5005661488 @default.
- W2535873244 creator A5046597133 @default.
- W2535873244 creator A5065853944 @default.
- W2535873244 creator A5071761978 @default.
- W2535873244 date "2016-10-31" @default.
- W2535873244 modified "2023-10-16" @default.
- W2535873244 title "Simulating Protein Fold Switching by Replica Exchange with Tunneling" @default.
- W2535873244 cites W1966078827 @default.
- W2535873244 cites W1968654669 @default.
- W2535873244 cites W1969554454 @default.
- W2535873244 cites W1973459793 @default.
- W2535873244 cites W1978993038 @default.
- W2535873244 cites W1983301339 @default.
- W2535873244 cites W1997665816 @default.
- W2535873244 cites W2000011436 @default.
- W2535873244 cites W2004560375 @default.
- W2535873244 cites W2012896985 @default.
- W2535873244 cites W2020353121 @default.
- W2535873244 cites W2020716464 @default.
- W2535873244 cites W2030081405 @default.
- W2535873244 cites W2031198154 @default.
- W2535873244 cites W2033793510 @default.
- W2535873244 cites W2036872878 @default.
- W2535873244 cites W2040809566 @default.
- W2535873244 cites W2041189078 @default.
- W2535873244 cites W2043432627 @default.
- W2535873244 cites W2044882887 @default.
- W2535873244 cites W2047510784 @default.
- W2535873244 cites W2048696758 @default.
- W2535873244 cites W2050219998 @default.
- W2535873244 cites W2052630662 @default.
- W2535873244 cites W2053655346 @default.
- W2535873244 cites W2056993402 @default.
- W2535873244 cites W2057477511 @default.
- W2535873244 cites W2059013803 @default.
- W2535873244 cites W2061844749 @default.
- W2535873244 cites W2065281489 @default.
- W2535873244 cites W2069860285 @default.
- W2535873244 cites W2083128709 @default.
- W2535873244 cites W2086817352 @default.
- W2535873244 cites W2090631659 @default.
- W2535873244 cites W2096344315 @default.
- W2535873244 cites W2105717859 @default.
- W2535873244 cites W2107656097 @default.
- W2535873244 cites W2114438007 @default.
- W2535873244 cites W2122220546 @default.
- W2535873244 cites W2134782652 @default.
- W2535873244 cites W2135965992 @default.
- W2535873244 cites W2144562104 @default.
- W2535873244 cites W2160721947 @default.
- W2535873244 cites W2161605421 @default.
- W2535873244 cites W2163126567 @default.
- W2535873244 cites W2164270482 @default.
- W2535873244 cites W2194026071 @default.
- W2535873244 cites W2332252149 @default.
- W2535873244 cites W3101006260 @default.
- W2535873244 cites W3104163644 @default.
- W2535873244 cites W4230808818 @default.
- W2535873244 doi "https://doi.org/10.1021/acs.jctc.6b00826" @default.
- W2535873244 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27767301" @default.
- W2535873244 hasPublicationYear "2016" @default.
- W2535873244 type Work @default.
- W2535873244 sameAs 2535873244 @default.
- W2535873244 citedByCount "28" @default.
- W2535873244 countsByYear W25358732442017 @default.
- W2535873244 countsByYear W25358732442018 @default.
- W2535873244 countsByYear W25358732442019 @default.
- W2535873244 countsByYear W25358732442020 @default.
- W2535873244 countsByYear W25358732442022 @default.
- W2535873244 crossrefType "journal-article" @default.
- W2535873244 hasAuthorship W2535873244A5005661488 @default.
- W2535873244 hasAuthorship W2535873244A5046597133 @default.
- W2535873244 hasAuthorship W2535873244A5065853944 @default.
- W2535873244 hasAuthorship W2535873244A5071761978 @default.
- W2535873244 hasConcept C104317684 @default.
- W2535873244 hasConcept C11413529 @default.
- W2535873244 hasConcept C142362112 @default.
- W2535873244 hasConcept C153349607 @default.
- W2535873244 hasConcept C185592680 @default.
- W2535873244 hasConcept C199360897 @default.
- W2535873244 hasConcept C204328495 @default.
- W2535873244 hasConcept C2775937380 @default.
- W2535873244 hasConcept C2986374874 @default.
- W2535873244 hasConcept C41008148 @default.
- W2535873244 hasConcept C53942344 @default.
- W2535873244 hasConcept C55439883 @default.
- W2535873244 hasConcept C55493867 @default.
- W2535873244 hasConcept C70721500 @default.
- W2535873244 hasConcept C86803240 @default.
- W2535873244 hasConceptScore W2535873244C104317684 @default.
- W2535873244 hasConceptScore W2535873244C11413529 @default.
- W2535873244 hasConceptScore W2535873244C142362112 @default.
- W2535873244 hasConceptScore W2535873244C153349607 @default.
- W2535873244 hasConceptScore W2535873244C185592680 @default.
- W2535873244 hasConceptScore W2535873244C199360897 @default.
- W2535873244 hasConceptScore W2535873244C204328495 @default.