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- W2536231091 abstract "To evaluate the relationship between maternal age at child birth, and perinatal and under-five mortality. Prospective birth cohort. Urban community. 9169 pregnancies in the New Delhi Birth Cohort resulted in 8181 live births. These children were followed for survival status and anthropometric measurements at birth (+3 days), 3,6,9 and 12 months (7 days), and every 6 months thereafter until 21 years age. Information on maternal age at child birth and socio-demographic profile was also obtained. Offspring mortality from 28 weeks gestation till 5 years age. Offspring mortality (stillbirths–5 years; n=328) had a U-shaped association with maternal age (P<0.001). Compared to the reference group (20-24 years), younger (≤19 years) and older (≥ 35 years) maternal ages were associated with a higher risk of offspring mortality (HR: 1.68; 95% CI 1.16, 2.43 and HR 1.48; 95% CI 1.01, 2.16, respectively). In young mothers, the increased risk persisted after adjustment for socio-economic confounders (maternal education, household income and wealth; HR 1.51; 95% CI 1.03, 2.20) and further for additional behavioral (place of delivery) and biological mediators (gestation and birthweight) (HR 2.14; 95% CI 1.25,3.64). Similar associations were documented for post-perinatal deaths but for perinatal mortality the higher risk was not statistically significant (P >0.05). In older mothers, the increased mortality risk was not statistically significant (P >0.05) after adjustment for socio-economic confounders. Young motherhood is associated with an increased risk of post-perinatal mortality and measures to prevent early childbearing should be strengthened." @default.
- W2536231091 created "2016-10-28" @default.
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- W2536231091 date "2016-10-01" @default.
- W2536231091 modified "2023-10-14" @default.
- W2536231091 title "Maternal age at childbirth and perinatal and under-five mortality in a prospective birth cohort from Delhi" @default.
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- W2536231091 doi "https://doi.org/10.1007/s13312-016-0950-9" @default.
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