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- W2536590375 abstract "Primary headaches and visceral pain are both very frequent medical conditions in the general population. Epidemiologic studies indicate that they very often coexist. Particularly frequent is the comorbidity between migraine and cardiac ischemic pain and between migraine/tension-type headache and functional gastrointestinal disorders, particularly irritable bowel syndrome (IBS). In women, overlap exists between migraine, dysmenorrhea, primary or secondary to endometriosis and interstitial cystitis/painful bladder syndrome (IC/PBS). The pathophysiology of these frequent associations remains elusive. Comorbidity between cardiac pain and migraine is probably based on an endothelial dysfunction common to both migraine and atherosclerosis, the major cause of ischemic cardiac pain. For IBS, dysmenorrhea and IC/PBS, a common likely mechanism is that of central sensitization, present in all conditions, as testified clinically by a generalized increase in pain sensitivity not only in painful but also non-painful areas. This chapter addresses the general epidemiology of visceral pain-headache comorbidities focusing on the clinical characteristics and therapeutic challenges posed by the most frequently encountered associations." @default.
- W2536590375 created "2016-10-28" @default.
- W2536590375 creator A5054250912 @default.
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- W2536590375 date "2016-10-25" @default.
- W2536590375 modified "2023-09-27" @default.
- W2536590375 title "Visceral Pain Comorbidity in Headache" @default.
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- W2536590375 doi "https://doi.org/10.1007/978-3-319-41454-6_4" @default.
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