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- W25374807 abstract "Aim:nTo evaluate the associations between birthweight and DM inthe general Australian population.Methods:nQuestions about birthweight by self-report were added tothe second round of the AusDiab study, which is a cross sectionalstudy of a nationwide stratified sample of 11 247 Australians aged25 years or over. This study presents analysis of survey results fromVictoria. Fasting plasma glucose (FPG) and glycosated haemoglobin(HbA1c) were modelled against birthweight as a continuous variableand a categorical variable of low birthweight (LBW), l3 kg. HighHbA1c was defined as HbA1c D7 mmol/L and high FPG as FPGg6.9 mmol/L.Results:nFive hundred and thirty three of 815 participants reportedtheir birthweight, and 480 considered their birthweight estimate reliable.Of these, Birthweights ranged from 1.0 to 5.9 kg with a mean(SD) of 3.4 (0.6) kg, and 117 were of LBW. After adjustment forage and sex, FPG and HbA1c were strongly correlated with birthweightand the relationship was strengthened with adjustment forphysical activity and current body weight. For each kg of higherbirthweight, with adjustment for age and sex, the OR (95% CI) forhigh FPG and high HbA1c for each kg of birthweight were 0.39(0.18n0.87), P = 0.02 and 0.62 (0.41n0.96) P = 0.03 respectively.The OR for LBW people of high FPG was 2.4 (1.2n4.6), P = 0.01and of high HbA1c was 7.2 (1.9n27.6), P = 0.004.Conclusion:nLBW was associated with a higher risk of developingDM in this cohort, with and without accounting for current weight." @default.
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- W25374807 date "2006-01-01" @default.
- W25374807 modified "2023-09-27" @default.
- W25374807 title "Glucose disorders and birthweight: results from the AusDiab Study" @default.
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