FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2537577462> ?p ?o ?g. }

• W2537577462 abstract "Developing networks of neural systems can exhibit spontaneous, synchronous activities called neural bursts, which can be important in the organization of functional neural circuits. Before the network matures, the activity level of a burst can reverberate in repeated rise-and-falls in periods of hundreds of milliseconds following an initial wave-like propagation of spiking activity, while the burst itself lasts for seconds. To investigate the spatiotemporal structure of the reverberatory bursts, we culture dissociated, rat cortical neurons on a high-density multi-electrode array to record the dynamics of neural activity over the growth and maturation of the network. We find the synchrony of the spiking significantly reduced following the initial wave and the activities become broadly distributed spatially. The synchrony recovers as the system reverberates until the end of the burst. Using a propagation model we infer the spreading speed of the spiking activity, which increases as the culture ages. We perform computer simulations of the system using a physiological model of spiking networks in two spatial dimensions and find the parameters that reproduce the observed resynchronization of spiking in the bursts. An analysis of the simulated dynamics suggests that the depletion of synaptic resources causes the resynchronization. The spatial propagation dynamics of the simulations match well with observations over the course of a burst and point to an interplay of the synaptic efficacy and the noisy neural self-activation in producing the morphology of the bursts." @default.
• W2537577462 created "2016-10-28" @default.
• W2537577462 creator A5049999221 @default.
• W2537577462 creator A5050869949 @default.
• W2537577462 creator A5083588122 @default.
• W2537577462 creator A5084952934 @default.
• W2537577462 date "2016-12-09" @default.
• W2537577462 modified "2023-10-01" @default.
• W2537577462 title "Propagation and synchronization of reverberatory bursts in developing cultured networks" @default.
• W2537577462 cites W1527468221 @default.
• W2537577462 cites W1529448825 @default.
• W2537577462 cites W1578782149 @default.
• W2537577462 cites W1963806203 @default.
• W2537577462 cites W1970885580 @default.
• W2537577462 cites W1985820929 @default.
• W2537577462 cites W1986408320 @default.
• W2537577462 cites W1989027959 @default.
• W2537577462 cites W1989276285 @default.
• W2537577462 cites W1996678516 @default.
• W2537577462 cites W2002429132 @default.
• W2537577462 cites W2010371447 @default.
• W2537577462 cites W2015701831 @default.
• W2537577462 cites W2017864163 @default.
• W2537577462 cites W2020850910 @default.
• W2537577462 cites W2025772448 @default.
• W2537577462 cites W2031543773 @default.
• W2537577462 cites W2035206083 @default.
• W2537577462 cites W2036984726 @default.
• W2537577462 cites W2038769137 @default.
• W2537577462 cites W2044773242 @default.
• W2537577462 cites W2046424015 @default.
• W2537577462 cites W2053850015 @default.
• W2537577462 cites W2056734624 @default.
• W2537577462 cites W2058874466 @default.
• W2537577462 cites W2064241002 @default.
• W2537577462 cites W2066763305 @default.
• W2537577462 cites W2069306062 @default.
• W2537577462 cites W2087727099 @default.
• W2537577462 cites W2090281903 @default.
• W2537577462 cites W2095900722 @default.
• W2537577462 cites W2096473662 @default.
• W2537577462 cites W2102297429 @default.
• W2537577462 cites W2102338390 @default.
• W2537577462 cites W2105475977 @default.
• W2537577462 cites W2118635321 @default.
• W2537577462 cites W2127397642 @default.
• W2537577462 cites W2137125445 @default.
• W2537577462 cites W2141443763 @default.
• W2537577462 cites W2150497419 @default.
• W2537577462 cites W2154504257 @default.
• W2537577462 cites W2157241438 @default.
• W2537577462 cites W2157315491 @default.
• W2537577462 cites W2158446914 @default.
• W2537577462 cites W2161983882 @default.
• W2537577462 cites W2167809052 @default.
• W2537577462 cites W2168462263 @default.
• W2537577462 cites W3209401433 @default.
• W2537577462 doi "https://doi.org/10.1007/s10827-016-0634-4" @default.
• W2537577462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27942935" @default.
• W2537577462 hasPublicationYear "2016" @default.
• W2537577462 type Work @default.
• W2537577462 sameAs 2537577462 @default.
• W2537577462 citedByCount "5" @default.
• W2537577462 countsByYear W25375774622018 @default.
• W2537577462 countsByYear W25375774622019 @default.
• W2537577462 countsByYear W25375774622020 @default.
• W2537577462 countsByYear W25375774622023 @default.
• W2537577462 crossrefType "journal-article" @default.
• W2537577462 hasAuthorship W2537577462A5049999221 @default.
• W2537577462 hasAuthorship W2537577462A5050869949 @default.
• W2537577462 hasAuthorship W2537577462A5083588122 @default.
• W2537577462 hasAuthorship W2537577462A5084952934 @default.
• W2537577462 hasBestOaLocation W25375774622 @default.
• W2537577462 hasConcept C11731999 @default.
• W2537577462 hasConcept C118403218 @default.
• W2537577462 hasConcept C121332964 @default.
• W2537577462 hasConcept C127162648 @default.
• W2537577462 hasConcept C145912823 @default.
• W2537577462 hasConcept C154945302 @default.
• W2537577462 hasConcept C169760540 @default.
• W2537577462 hasConcept C195221683 @default.
• W2537577462 hasConcept C24890656 @default.
• W2537577462 hasConcept C2778562939 @default.
• W2537577462 hasConcept C2984127161 @default.
• W2537577462 hasConcept C41008148 @default.
• W2537577462 hasConcept C50644808 @default.
• W2537577462 hasConcept C76155785 @default.
• W2537577462 hasConcept C86803240 @default.
• W2537577462 hasConceptScore W2537577462C11731999 @default.
• W2537577462 hasConceptScore W2537577462C118403218 @default.
• W2537577462 hasConceptScore W2537577462C121332964 @default.
• W2537577462 hasConceptScore W2537577462C127162648 @default.
• W2537577462 hasConceptScore W2537577462C145912823 @default.
• W2537577462 hasConceptScore W2537577462C154945302 @default.
• W2537577462 hasConceptScore W2537577462C169760540 @default.
• W2537577462 hasConceptScore W2537577462C195221683 @default.
• W2537577462 hasConceptScore W2537577462C24890656 @default.
• W2537577462 hasConceptScore W2537577462C2778562939 @default.
• W2537577462 hasConceptScore W2537577462C2984127161 @default.
• W2537577462 hasConceptScore W2537577462C41008148 @default.

• next