FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2537584703> ?p ?o ?g. }

• W2537584703 endingPage "857" @default.
• W2537584703 startingPage "857" @default.
• W2537584703 abstract "We presented the colorimetric and electrochemical methods for determination of the dipeptidyl peptidase-IV (DPP-IV) activity and screening of its inhibitor using gold nanoparticle (AuNP) as the probe. In the colorimetric assay, the substrate peptide with a sequence of Arg-Pro-Arg induced the aggregation and color change of AuNPs, whereas cleavage of the peptide by DPP-IV prevented the aggregation of AuNPs. Furthermore, the aggregation of AuNPs in the solution was easily initiated on a solid/liquid (electrode/electrolyte) surface, which induced a decrease in the electron-transfer resistance. However, once the peptide was clipped by DPP-IV, the assembly of AuNPs on electrode surface was prevented. Consequently, a higher electron-transfer resistance was observed. The colorimetric and electrochemical assays allowed for the determination of DPP-IV with the detection limits of 70 μU/mL and 0.55 μU/mL, respectively. Meanwhile, the proposed methods were used to determine DPP-IV inhibitor with satisfactory results. Both the colorimetric and electrochemical methods are simple, rapid and sufficiently sensitive for DPP-IV activity assay and inhibitor screening. The results also demonstrated that the AuNP-based colorimetric assay could be converted into an enhanced surface tethered electrochemical assay with improving sensitivity. The simple detection principle may be extended to the design of other peptidases biosensors with easy manipulation procedures." @default.
• W2537584703 created "2016-10-28" @default.
• W2537584703 creator A5006204563 @default.
• W2537584703 creator A5006822602 @default.
• W2537584703 creator A5035648686 @default.
• W2537584703 creator A5079393710 @default.
• W2537584703 date "2016-10-21" @default.
• W2537584703 modified "2023-10-14" @default.
• W2537584703 title "Gold Nanoparticle-Based Colorimetric and Electrochemical Methods for Dipeptidyl Peptidase-IV Activity Assay and Inhibitor Screening" @default.
• W2537584703 cites W1252614118 @default.
• W2537584703 cites W1833775185 @default.
• W2537584703 cites W1900053044 @default.
• W2537584703 cites W1979232921 @default.
• W2537584703 cites W1984013219 @default.
• W2537584703 cites W1985043634 @default.
• W2537584703 cites W1988976004 @default.
• W2537584703 cites W1994222380 @default.
• W2537584703 cites W2001526873 @default.
• W2537584703 cites W2002661845 @default.
• W2537584703 cites W2013196408 @default.
• W2537584703 cites W2020777766 @default.
• W2537584703 cites W2028310736 @default.
• W2537584703 cites W2029082107 @default.
• W2537584703 cites W2033981868 @default.
• W2537584703 cites W2039525573 @default.
• W2537584703 cites W2048702576 @default.
• W2537584703 cites W2050445499 @default.
• W2537584703 cites W2053103992 @default.
• W2537584703 cites W2054831936 @default.
• W2537584703 cites W2061225555 @default.
• W2537584703 cites W2065092992 @default.
• W2537584703 cites W2081733901 @default.
• W2537584703 cites W2082062969 @default.
• W2537584703 cites W2097789662 @default.
• W2537584703 cites W2105153983 @default.
• W2537584703 cites W2109482745 @default.
• W2537584703 cites W2112532082 @default.
• W2537584703 cites W2113066154 @default.
• W2537584703 cites W2134000656 @default.
• W2537584703 cites W2141001024 @default.
• W2537584703 cites W2141574066 @default.
• W2537584703 cites W2148912983 @default.
• W2537584703 cites W2149461013 @default.
• W2537584703 cites W2151190288 @default.
• W2537584703 cites W2157788572 @default.
• W2537584703 cites W2158180922 @default.
• W2537584703 cites W2163523761 @default.
• W2537584703 cites W2171502349 @default.
• W2537584703 cites W2239025850 @default.
• W2537584703 cites W2295776413 @default.
• W2537584703 cites W2329867824 @default.
• W2537584703 cites W2463467188 @default.
• W2537584703 cites W2475192879 @default.
• W2537584703 cites W2508914292 @default.
• W2537584703 cites W2511077993 @default.
• W2537584703 cites W4241057416 @default.
• W2537584703 doi "https://doi.org/10.3390/ma9100857" @default.
• W2537584703 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5456591" @default.
• W2537584703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28773977" @default.
• W2537584703 hasPublicationYear "2016" @default.
• W2537584703 type Work @default.
• W2537584703 sameAs 2537584703 @default.
• W2537584703 citedByCount "14" @default.
• W2537584703 countsByYear W25375847032017 @default.
• W2537584703 countsByYear W25375847032018 @default.
• W2537584703 countsByYear W25375847032020 @default.
• W2537584703 countsByYear W25375847032021 @default.
• W2537584703 countsByYear W25375847032023 @default.
• W2537584703 crossrefType "journal-article" @default.
• W2537584703 hasAuthorship W2537584703A5006204563 @default.
• W2537584703 hasAuthorship W2537584703A5006822602 @default.
• W2537584703 hasAuthorship W2537584703A5035648686 @default.
• W2537584703 hasAuthorship W2537584703A5079393710 @default.
• W2537584703 hasBestOaLocation W25375847031 @default.
• W2537584703 hasConcept C104819515 @default.
• W2537584703 hasConcept C119128265 @default.
• W2537584703 hasConcept C123669783 @default.
• W2537584703 hasConcept C13965031 @default.
• W2537584703 hasConcept C147789679 @default.
• W2537584703 hasConcept C155672457 @default.
• W2537584703 hasConcept C160756335 @default.
• W2537584703 hasConcept C171250308 @default.
• W2537584703 hasConcept C17525397 @default.
• W2537584703 hasConcept C178790620 @default.
• W2537584703 hasConcept C181199279 @default.
• W2537584703 hasConcept C185592680 @default.
• W2537584703 hasConcept C18903297 @default.
• W2537584703 hasConcept C192562407 @default.
• W2537584703 hasConcept C21951064 @default.
• W2537584703 hasConcept C2777289219 @default.
• W2537584703 hasConcept C2779281246 @default.
• W2537584703 hasConcept C2781469919 @default.
• W2537584703 hasConcept C43617362 @default.
• W2537584703 hasConcept C52859227 @default.
• W2537584703 hasConcept C55493867 @default.
• W2537584703 hasConcept C68801617 @default.
• W2537584703 hasConcept C86803240 @default.
• W2537584703 hasConceptScore W2537584703C104819515 @default.

• next