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• W2537865956 endingPage "2044" @default.
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• W2537865956 abstract "The stereoselective 1,3-dipolar cycloaddition between allyl cyanide and a menthone-derived nitrone led to the desired isoxazolidine in good yield. Once the nitrile group transformed to an amidoxime group, the cyclocondensation of various aldehydes with chiral amidoxime led to unprecedented enantiopure 3-methylisoxazolidine-5-aryl-1,2,4-oxadiazoles. The menthone chiral auxiliary was then removed with acid hydrolysis. The new compounds were also screened for their in vitro antioxidant activity using DPPH and FRAP assays. Some of the compounds showed promising antioxidant activity." @default.
• W2537865956 created "2016-10-28" @default.
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• W2537865956 date "2016-10-18" @default.
• W2537865956 modified "2023-09-25" @default.
• W2537865956 title "Unprecedented stereoselective synthesis of 3-methylisoxazolidine-5-aryl-1,2,4-oxadiazoles via 1,3-dipolar cycloaddition and study of their in vitro antioxidant activity" @default.
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• W2537865956 doi "https://doi.org/10.1080/00397911.2016.1244692" @default.
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