Matches in SemOpenAlex for { <https://semopenalex.org/work/W2539069755> ?p ?o ?g. }
- W2539069755 endingPage "171" @default.
- W2539069755 startingPage "163" @default.
- W2539069755 abstract "Human heat shock protein Hsp70 was experimentally inserted into polyelectrolyte microcapsules. Encapsulated recombinant Hsp70 was studied in terms of its effects on neutrophil apoptosis, the production of reactive oxygen species, and the secretion of tumor necrosis factor alpha by promonocytic THP-1 cells. It was found that encapsulated Hsp70 effectively inhibits neutrophil apoptosis, unlike free exogenous protein used in solution. In THP-1 cells, encapsulated and free Hsp70 reduced LPS-induced tumor necrosis factor alpha production with a similar efficiency. Encapsulated Hsp70 reduces LPS-induced reactive oxygen species production by neutrophils in the course of its release from the microcapsules but not as much as free Hsp70. Thus, the polyelectrolyte microcapsules can be used as containers for the effective delivery of Hsp70 to neutrophils and monocytes to significantly improve the functioning of the innate immune system." @default.
- W2539069755 created "2016-10-28" @default.
- W2539069755 creator A5015128883 @default.
- W2539069755 creator A5023848026 @default.
- W2539069755 creator A5035231992 @default.
- W2539069755 creator A5048453817 @default.
- W2539069755 creator A5087267915 @default.
- W2539069755 creator A5090637711 @default.
- W2539069755 creator A5091675673 @default.
- W2539069755 date "2016-10-26" @default.
- W2539069755 modified "2023-10-09" @default.
- W2539069755 title "Encapsulated Hsp70 decreases endotoxin-induced production of ROS and TNFα in human phagocytes" @default.
- W2539069755 cites W106564803 @default.
- W2539069755 cites W148231546 @default.
- W2539069755 cites W1531703039 @default.
- W2539069755 cites W1532279191 @default.
- W2539069755 cites W1581409175 @default.
- W2539069755 cites W1595587273 @default.
- W2539069755 cites W1608004049 @default.
- W2539069755 cites W1889187625 @default.
- W2539069755 cites W1899777911 @default.
- W2539069755 cites W1971206431 @default.
- W2539069755 cites W1977220348 @default.
- W2539069755 cites W1978427907 @default.
- W2539069755 cites W1984472423 @default.
- W2539069755 cites W1999667172 @default.
- W2539069755 cites W2016906514 @default.
- W2539069755 cites W2019107340 @default.
- W2539069755 cites W2025838935 @default.
- W2539069755 cites W2035306303 @default.
- W2539069755 cites W2038427475 @default.
- W2539069755 cites W2048736491 @default.
- W2539069755 cites W2049438990 @default.
- W2539069755 cites W2056856535 @default.
- W2539069755 cites W2060668169 @default.
- W2539069755 cites W2062346797 @default.
- W2539069755 cites W2065569312 @default.
- W2539069755 cites W2068818475 @default.
- W2539069755 cites W2073754785 @default.
- W2539069755 cites W2073821065 @default.
- W2539069755 cites W2074009827 @default.
- W2539069755 cites W2077743495 @default.
- W2539069755 cites W2085371831 @default.
- W2539069755 cites W2089385363 @default.
- W2539069755 cites W2089475053 @default.
- W2539069755 cites W2091226790 @default.
- W2539069755 cites W2094605832 @default.
- W2539069755 cites W2095249660 @default.
- W2539069755 cites W2095497639 @default.
- W2539069755 cites W2108244203 @default.
- W2539069755 cites W2110299641 @default.
- W2539069755 cites W2110586410 @default.
- W2539069755 cites W2111389066 @default.
- W2539069755 cites W2120452971 @default.
- W2539069755 cites W2128635872 @default.
- W2539069755 cites W2145577370 @default.
- W2539069755 cites W2170449219 @default.
- W2539069755 cites W2171260748 @default.
- W2539069755 cites W2236028734 @default.
- W2539069755 cites W2270421926 @default.
- W2539069755 cites W2274487043 @default.
- W2539069755 cites W2285170750 @default.
- W2539069755 cites W2315844657 @default.
- W2539069755 cites W2320328374 @default.
- W2539069755 cites W2326812759 @default.
- W2539069755 cites W2333282498 @default.
- W2539069755 cites W2345994250 @default.
- W2539069755 cites W4293247451 @default.
- W2539069755 doi "https://doi.org/10.1007/s12192-016-0743-z" @default.
- W2539069755 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5225061" @default.
- W2539069755 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27783274" @default.
- W2539069755 hasPublicationYear "2016" @default.
- W2539069755 type Work @default.
- W2539069755 sameAs 2539069755 @default.
- W2539069755 citedByCount "9" @default.
- W2539069755 countsByYear W25390697552019 @default.
- W2539069755 countsByYear W25390697552020 @default.
- W2539069755 countsByYear W25390697552021 @default.
- W2539069755 countsByYear W25390697552022 @default.
- W2539069755 crossrefType "journal-article" @default.
- W2539069755 hasAuthorship W2539069755A5015128883 @default.
- W2539069755 hasAuthorship W2539069755A5023848026 @default.
- W2539069755 hasAuthorship W2539069755A5035231992 @default.
- W2539069755 hasAuthorship W2539069755A5048453817 @default.
- W2539069755 hasAuthorship W2539069755A5087267915 @default.
- W2539069755 hasAuthorship W2539069755A5090637711 @default.
- W2539069755 hasAuthorship W2539069755A5091675673 @default.
- W2539069755 hasBestOaLocation W25390697552 @default.
- W2539069755 hasConcept C104317684 @default.
- W2539069755 hasConcept C136449434 @default.
- W2539069755 hasConcept C17991360 @default.
- W2539069755 hasConcept C185592680 @default.
- W2539069755 hasConcept C190283241 @default.
- W2539069755 hasConcept C203014093 @default.
- W2539069755 hasConcept C205260736 @default.
- W2539069755 hasConcept C48349386 @default.
- W2539069755 hasConcept C49039625 @default.
- W2539069755 hasConcept C55493867 @default.