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- W2539570655 abstract "With the recent introduction of hybrid SPECT/CT systems, with diagnostic multi-slice CT (Computed Tomography) capabilities the CT dose delivered to the patient may become an issue, as compensation in SPECT using co-registered CT data becomes more common in clinical practice. In general, any CT data can be converted to a volume of linear coefficients (LAC), also referred to as the attenuation map, or mu-map. We investigated the range of CT settings that minimize the dose to the patient and allow for CT image quality that is appropriate for correction. SPECT/CT registration issues are outside the scope of this work, and we assume that the objects are perfectly registered. Various phantoms are used to analyze both CT and attenuation-corrected SPECT image quality, where the CT data itself is used to generate the mu-maps. Conclusion: The effective dose to the patient from a CT scan for the purpose of SPECT AC can be lowered to at least 30% to 50% without affecting the image quality of the SPECT AC, using CT derived mu-maps, if an appropriate scan protocol with a very smooth (MTF at 50%: 1.0 Ip/cm) CT reconstruction kernel is used. A further clinical investigation is needed to confirm these findings in clinical practice" @default.
- W2539570655 created "2016-11-04" @default.
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- W2539570655 date "2005-08-10" @default.
- W2539570655 modified "2023-09-25" @default.
- W2539570655 title "Method to minimize dose for CT attenuation correction in SPECT" @default.
- W2539570655 cites W2014296809 @default.
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- W2539570655 doi "https://doi.org/10.1109/nssmic.2004.1466300" @default.
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