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• W2540189362 startingPage "285" @default.
• W2540189362 abstract "This chapter intends to introduce the reader to current approaches to targeted treatment for type 1 diabetes (T1D) with the current gold standard clinical therapies that are now offered. In particular, it reviews the most successful transplant techniques for patients with type 1 diabetes and secondary complications. It also provides an in-depth insight into the new frontiers in β-islet cell replacement showing the newest and most novel ways in which scientists and clinicians are now targeting the development of insulin-producing cells in the laboratory, which remains a major focus to finding a cure for type 1 diabetes. This chapter focuses specifically on the newest genetic engineering methods to prevent the onset of diabetes at various stages by a number of techniques to provide numerous ways to produce surrogate β-cells to replace a patient’s own destroyed islet cells. These technologies discussed also include genetic manipulation of the patient’s own cells to produce insulin or ways and techniques to substitute them with the latest types of β-islet cell replacement. These arise in the form of xeno-islet cell transplants and the novel ways by which to prevent their rejection. This ultimately has the ability to achieve the Holy Grail of permanently curing a patient of their type 1 diabetes ." @default.
• W2540189362 created "2016-11-04" @default.
• W2540189362 creator A5045746547 @default.
• W2540189362 date "2016-01-01" @default.
• W2540189362 modified "2023-10-12" @default.
• W2540189362 title "Beta Cell Therapies for Type 1 Diabetes" @default.
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