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- W2541321694 abstract "A method for the simple demonstration of leucocidin specific for human blood cells was elaborated, by means of differential staining of killed and living leucocytes. The titre of specific leucocidin was determined in 476 strains, and the titre of alpha-toxin in 542 strains, all of different origin. In the case of alpha-toxin there is no difference in the titre in strains of different origin. In the case of specific leucocidin, strains isolated from a pathological process form far more leucoeidin than strains isolated from healthy subjects. There is a statistically significant correlation between the titre of the leucocidin and the degree of severity of the desease evoked by the strains in question. The characteristics of the strains isolated from healthy subjects show that this is a non-homogenous group, which contains both banal carriers of only slightly pathogenic staphylococci and also carriers of strains with the same properties as those isolated from infections. These results demonstrate the possibility of diagnosing particularly virulent and dangerous strains of staphylococci according to the production of leucocidin. When preparing a toxoid and staphylococcal serum for therapeutic purposes, the strains and also the methods should be selected not only according the titration of alpha-toxin but also according to the production of specific leucocidin." @default.
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- W2541321694 date "1957-01-01" @default.
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- W2541321694 title "The significance of staphylococcal α toxin and leucocidin" @default.
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