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• W2541403156 abstract "Ataxia-telangiectasia (AT) is characterized by cerebellar ataxia, progressive immunodeficiency, radiation sensitivity, telangiectasia, and predisposition to malignancy. AT patients have a 100-fold increased risk for the development of lymphoid malignancies. It is important to consider AT in a child with pre-existing ataxia, or lymphoid malignancy that was diagnosed at a younger age than expected. This consideration avoids the confusion between ataxia development and toxicity from chemotherapy. Hodgkin ’s lymphoma (HL) is usually treated with chemotherapy and/or radiotherapy. Unfortunately, when treated with conventional doses of radiotherapy, AT patients invariably experience devastating necrosis of their normal tissues. Therefore, a new treatment protocol for patients with HL in AT must be established. In this paper, we report the case of an 8-year-old female patient with HL in AT who was treated with chemotherapy. This patient was also treated with brentuximab (which targets CD30) for salvage therapy after the disease" @default.
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• W2541403156 date "2016-10-31" @default.
• W2541403156 modified "2023-09-28" @default.
• W2541403156 title "A Case of Hodgkin Lymphoma Developed in an Ataxia-telangiectasia Patient" @default.
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• W2541403156 doi "https://doi.org/10.15264/cpho.2016.23.2.184" @default.
• W2541403156 hasPublicationYear "2016" @default.
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