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- W25423649 abstract "3 OZET: Otistik spektrum bozukluu tan›l› dokuz yafl›n- da bir olguda fluoksetin kullan›m›na bal› fe- kal inkontinans: Bir olgu sunumu Yayg›n geliflimsel bozukluk (YGB) tan›l› cocuk ve ergenler- de selektif serotonin geri al›m inhibitor'lerinin (SSG‹) kulla- n›m›ndaki belirgin art›fla ramen, yap›lan araflt›rmalar›n co- ¤unluu YGB hastalar›n›n bu ilaclara dufluk oranda tolera- bilite gosterdiini ortaya koymufltur. SSG‹'lerle gorulen ters ilac etkileri aras›nda gastrointestinal yan etkiler (G‹S-YE) s›k- t›r ve genellikle hafif ve kendini s›n›rlay›c› niteliktedir. YGB tan›l› cocuklarda gastrointestinal flikayetler s›k olarak izlen- mektedir. Her ne kadar onceden gosterilmemiflse de, YGB'li cocuklar SSG‹'lerin ciddi G‹S-YE'ne daha yatk›n olabilirler. Bu olgu sunumunda, 9 yafl›nda YGB, baflka turlu adland›r›- lamayan (YGB-BTA) tan›l› bir olguda fluoksetin kullan›m› ile, ilac›n kesimine yol acan, fekal inkontinans gelifliminden bahsedilecektir. Klinisyenler YGB tan›l› cocuklarda SSG‹ kul- lan›rken ciddi G‹S-YE ac›s›ndan dikkatli olmal›d›r. Anahtar sozcukler: Fluoksetin, fekal inkontinans, SSG‹, YGB, cocuk Klinik Psikofarmakoloji Bulteni 2009;19:289-293 ABSTRACT: induced fecal incontinence in a 9 year old child with autistic spectrum disorder: a case report Despite the dramatic rise in the use of selective serotonin reuptake inhibitors (SSRIs) in children and adolescents with pervasive developmental disorders (PDD) in recent years, the majority of studies of SSRI use in PDD population demonstrated lower tolerability compared to children without PDD. Among the adverse reactions to SSRI use, gastrointestinal adverse effects (GIS-AE) are common and usually reported to be mild and self limited. Children with PDD are shown to have higher rates of gastrointestinal symptoms including stool inconsistencies than the general childhood population and although not previously shown, they may be more vulnerable to severe GIS-AE of SSRIs. We present a case of a 9 year old girl with PDD not otherwise specified (PDD-NOS) who developed fecal incontinence (FI) in the treatment of fluoxetine which led to the discontinuation of the agent. Clinicians must be aware of severe GIS-AE when using SSRIs in children with PDD." @default.
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- W25423649 date "2009-01-01" @default.
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- W25423649 title "Fluoxetine induced fecal incontinence in a 9 year old child with autistic spectrum disorder: a case report -" @default.
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