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• W2542557306 abstract "Introduction: Les objectifs de notre travail sont d’evaluer l’impact pronostic de la profondeur d’infiltration tumorale du chorion et de l’envahissement ou non de la musculaire muqueuse des tumeurs pT1 de la vessie en etudiant les taux de recidive et de progression, les survies globale, sans recidive et sans progression. Patients et Methodes: La relecture de toutes les lames a ete effectuee pour determiner la presence ou non de la musculaire muqueuse, son envahissement (pT1b) ou non (pT1a) et la profondeur d’envahissement du chorion (pT1 m: envahissement unifocal ≤ 0,5 mm ou pT1e: envahissement unifocal > 0,5 mm ou multiple). Resultats: En fonction de l’invasion de la musculaire muqueuse, les taux de recidive et de progression etaient plus frequents pour les tumeurs pT1b par rapport a celles pT1a, avec un taux de recidive de 84.6% (p = 0,0012) et de progression de 38.5% (p = 0,003). En fonction du degre d’invasion du chorion, la recidive et la progression etaient plus frequentes pour les tumeurs pT1e par rapport a celles pT1 m (respectivement 57.2 (p = 0,05) et 17.9% (p = 0.11)). La survie moyenne sans recidive etait de 70.3 mois pour les tumeurs pT1a et 53.6 mois pour celles pT1b (p = 0,046), et elle etait de 61.7 mois pour les tumeurs pT1e et de 55.5 mois pour celles pT1 m (p = 0,85). Conclusion: Le classement des ces tumeurs en fonction de l’importance d’envahissement du chorion et del’infiltration de la musculaire muqueuse a prouve son efficacite a travers les taux de recidive et de progressiontumorale chez nos malades. Mots cles:  tumeur vesicale; survie; recidive; progression de la maladie English Title:  Prognostic interest of tumoral infiltration depth of chorion in the evolution of pT1 bladder tumors English Abstract Introduction: The aim of our study was to evaluate the prognostic impact of tumor infiltration depth of the lamina propria and invasion or non-invasion of the muscularis mucosa of pT1 bladder tumors, studyingrecurrence and progression rate, overall survival, disease-free survival and progression-free survival. Patients and methods: All slides were reviewed to determine the presence or absence of muscularis mucosa,invasion above (pT1a) or below (pT1b) the muscularis mucosa, and the invasion depth of the lamina propria (pT1m: a single focus of lamina propria invasion ≤0.5 mm, pT1e: single focus >0.5 mm of lamina propriainvasion or multiple micro-invasive area). Results: Depending on the invasion of the muscularis mucosa, the rate of recurrence and progression wasmore frequent in pT1b tumors in comparison to patients classified pT1a, with a recurrence rate of 84.6% ( p = 0.0012) and a progression rate of 38.5% ( p = 0.003). Depending on the degree of invasion of the laminapropria, the rate of recurrence and progression was more frequent for pT1e tumors in comparison to pT1m,with a recurrence rate of 57.2% ( p = 0.05) and a progression rate of 17.9% ( p = 0.11). Disease-free survivalwas 70.3 months for pT1a tumors against 53.6 months for pT1b tumors ( p = 0.046), and it was 61.7 monthsfor pT1e tumors against 55.5 months for pT1m tumors ( p = 0.85). Conclusion: The classification of bladder tumors based on the invasion of the lamina propria has provedits efficiency through the recurrence rate and the progression rate among our patients. Keywords:  urinary bladder neoplasms, survival analysis, recurrence, disease progression" @default.
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• W2542557306 date "2016-12-01" @default.
• W2542557306 modified "2023-09-28" @default.
• W2542557306 title "Intérêt pronostique de l’infiltration du chorion dans les tumeurs vésicales pT1" @default.
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• W2542557306 doi "https://doi.org/10.1016/j.afju.2016.05.006" @default.
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