FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2543287839> ?p ?o ?g. }

• W2543287839 abstract "The use of expanded criteria donor (ECD) kidneys has increased the overall availability of renal transplants. This study assessed the use of sirolimus in patients receiving Argentina-ECD kidneys.This observational, open-label, 1-arm, prospective, longitudinal pilot study was conducted at 8 transplant centers in Argentina. Adults receiving kidney transplants (without pancreas) from ECDs were eligible if they were converted to sirolimus 1 to 36 months' posttransplantation, with sirolimus becoming base therapy within 1 month after conversion. Patients were followed up for 1 year. Outcomes included reasons for conversion, acute rejection, patient and graft survival, graft status, and safety.The intention-to-treat population included 52 patients (mean age, 48.7 years). Calcineurin inhibitor nephropathy (40%) and chronic allograft nephropathy (25%) were the most frequent reasons for conversion. Two acute rejections occurred during follow-up, but no patients experienced graft loss. One patient died during follow-up, and 3 patients died within 1 month of the last sirolimus dose. Levels of serum creatinine and creatinine clearance remained stable from baseline to week 52/53. Mean proteinuria measured in a subset of patients was 0.2 ± 0.2 g/24 hours before conversion and increased to 0.6 ± 1.2 g/24 hours at week 24/25 and 0.5 ± 0.6 g/24 hours at week 52/53. Adverse events were consistent with those in previous conversion trials; the most common were infections and infestations (54%).This pilot study illustrates the potential benefits of sirolimus in recipients of ECD kidneys in Argentina. Larger, randomized controlled trials are needed to confirm these findings and to clarify the long-term benefits of sirolimus in this patient population." @default.
• W2543287839 created "2016-11-04" @default.
• W2543287839 creator A5006619783 @default.
• W2543287839 creator A5014737398 @default.
• W2543287839 creator A5031710336 @default.
• W2543287839 creator A5035174094 @default.
• W2543287839 creator A5041553552 @default.
• W2543287839 creator A5043629474 @default.
• W2543287839 creator A5045277386 @default.
• W2543287839 creator A5054745339 @default.
• W2543287839 creator A5057340060 @default.
• W2543287839 creator A5067717329 @default.
• W2543287839 creator A5071888509 @default.
• W2543287839 date "2016-10-01" @default.
• W2543287839 modified "2023-09-26" @default.
• W2543287839 title "Surveillance Registry of Sirolimus Use in Recipients of Kidney Allografts From Expanded Criteria Donors" @default.
• W2543287839 cites W1566056826 @default.
• W2543287839 cites W1842004637 @default.
• W2543287839 cites W1969510397 @default.
• W2543287839 cites W1974844984 @default.
• W2543287839 cites W2020368170 @default.
• W2543287839 cites W2022946218 @default.
• W2543287839 cites W2032593110 @default.
• W2543287839 cites W2057399858 @default.
• W2543287839 cites W2077666019 @default.
• W2543287839 cites W2085589627 @default.
• W2543287839 cites W2122595487 @default.
• W2543287839 cites W2145337089 @default.
• W2543287839 doi "https://doi.org/10.1016/j.transproceed.2016.08.008" @default.
• W2543287839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27788796" @default.
• W2543287839 hasPublicationYear "2016" @default.
• W2543287839 type Work @default.
• W2543287839 sameAs 2543287839 @default.
• W2543287839 citedByCount "2" @default.
• W2543287839 countsByYear W25432878392018 @default.
• W2543287839 countsByYear W25432878392020 @default.
• W2543287839 crossrefType "journal-article" @default.
• W2543287839 hasAuthorship W2543287839A5006619783 @default.
• W2543287839 hasAuthorship W2543287839A5014737398 @default.
• W2543287839 hasAuthorship W2543287839A5031710336 @default.
• W2543287839 hasAuthorship W2543287839A5035174094 @default.
• W2543287839 hasAuthorship W2543287839A5041553552 @default.
• W2543287839 hasAuthorship W2543287839A5043629474 @default.
• W2543287839 hasAuthorship W2543287839A5045277386 @default.
• W2543287839 hasAuthorship W2543287839A5054745339 @default.
• W2543287839 hasAuthorship W2543287839A5057340060 @default.
• W2543287839 hasAuthorship W2543287839A5067717329 @default.
• W2543287839 hasAuthorship W2543287839A5071888509 @default.
• W2543287839 hasConcept C126322002 @default.
• W2543287839 hasConcept C126894567 @default.
• W2543287839 hasConcept C128057223 @default.
• W2543287839 hasConcept C141071460 @default.
• W2543287839 hasConcept C159641895 @default.
• W2543287839 hasConcept C188816634 @default.
• W2543287839 hasConcept C197934379 @default.
• W2543287839 hasConcept C2777921159 @default.
• W2543287839 hasConcept C2779561371 @default.
• W2543287839 hasConcept C2780091579 @default.
• W2543287839 hasConcept C2780303639 @default.
• W2543287839 hasConcept C2780306776 @default.
• W2543287839 hasConcept C2908647359 @default.
• W2543287839 hasConcept C2911091166 @default.
• W2543287839 hasConcept C71924100 @default.
• W2543287839 hasConcept C99454951 @default.
• W2543287839 hasConceptScore W2543287839C126322002 @default.
• W2543287839 hasConceptScore W2543287839C126894567 @default.
• W2543287839 hasConceptScore W2543287839C128057223 @default.
• W2543287839 hasConceptScore W2543287839C141071460 @default.
• W2543287839 hasConceptScore W2543287839C159641895 @default.
• W2543287839 hasConceptScore W2543287839C188816634 @default.
• W2543287839 hasConceptScore W2543287839C197934379 @default.
• W2543287839 hasConceptScore W2543287839C2777921159 @default.
• W2543287839 hasConceptScore W2543287839C2779561371 @default.
• W2543287839 hasConceptScore W2543287839C2780091579 @default.
• W2543287839 hasConceptScore W2543287839C2780303639 @default.
• W2543287839 hasConceptScore W2543287839C2780306776 @default.
• W2543287839 hasConceptScore W2543287839C2908647359 @default.
• W2543287839 hasConceptScore W2543287839C2911091166 @default.
• W2543287839 hasConceptScore W2543287839C71924100 @default.
• W2543287839 hasConceptScore W2543287839C99454951 @default.
• W2543287839 hasFunder F4320307765 @default.
• W2543287839 hasLocation W25432878391 @default.
• W2543287839 hasLocation W25432878392 @default.
• W2543287839 hasOpenAccess W2543287839 @default.
• W2543287839 hasPrimaryLocation W25432878391 @default.
• W2543287839 hasRelatedWork W1522114158 @default.
• W2543287839 hasRelatedWork W1585110933 @default.
• W2543287839 hasRelatedWork W1796019961 @default.
• W2543287839 hasRelatedWork W1842995126 @default.
• W2543287839 hasRelatedWork W1992390933 @default.
• W2543287839 hasRelatedWork W2022093303 @default.
• W2543287839 hasRelatedWork W2030823235 @default.
• W2543287839 hasRelatedWork W2080160899 @default.
• W2543287839 hasRelatedWork W2088749847 @default.
• W2543287839 hasRelatedWork W2093702116 @default.
• W2543287839 hasRelatedWork W2117600377 @default.
• W2543287839 hasRelatedWork W2258802070 @default.
• W2543287839 hasRelatedWork W2398653975 @default.
• W2543287839 hasRelatedWork W2413264913 @default.
• W2543287839 hasRelatedWork W2423536502 @default.

• next