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- W2543862460 abstract "This study aims to critically appraise the reporting quality of pharmacoeconomic studies in breast cancer conducted in China and written in Chinese using Consolidated Health Economic Evaluation Reporting Standards (CHEERS) developed by ISPOR. A literature search was done using three Chinese databases of CNKI, Wanfang and CQvip to identify economic evaluations of breast cancer treatments published in China during January 2003 to September 2015. Two independent reviewers assessed the reporting quality of studies using the CHEERS checklist with 24 items, and a third reviewer was called upon to resolve any disagreement. Of the 25 pharmacoeconomic studies included, 96% were cost-effectiveness analyses, including one cost-utility analysis. The main source of effectiveness data was medical records in 68% of studies, while other sources included clinical trials, expert opinions, and literature reviews. On average, 30% (range: 15%-63%) of the checklist items were met, however, 25% (11%-26%) items were not applicable, including “measurement and valuation of preference based outcomes”, “choice of model”, “assumptions”, synthesis-based “measurement of effectiveness”, and three model-related items. Excluding the non-applicable items, a mean of 40% (20%-71%) of the checklist items were met by an average study. Over 80% of criteria related to “Methods” section were not met, including “measurement of effectiveness”, “discount rate”, “study perspective”, and “estimating resources and costs”. Further, “characterising heterogeneity”, “study parameters”, and “characterising uncertainty” in “Results” section were seldom mentioned. Only two items, “setting and location” and “choice of health outcomes” were met by all studies. Other items reported by over 75% of studies included “abstract”, “target population and subgroups”, “comparators”, and “incremental costs and outcomes”. Pharmacoeconomic studies of breast cancer treatments published in Chinese language were found to have a low reporting quality, with insufficient information about input data sources, healthcare resource utilization and costs in the methods section in particular." @default.
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- W2543862460 date "2016-11-01" @default.
- W2543862460 modified "2023-09-28" @default.
- W2543862460 title "The Quality of Pharmacoeconomic Publications in Breast Cancer Pharmacotherapies in China" @default.
- W2543862460 doi "https://doi.org/10.1016/j.jval.2016.08.096" @default.
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