FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2544388718> ?p ?o ?g. }

• W2544388718 endingPage "2475" @default.
• W2544388718 startingPage "2468" @default.
• W2544388718 abstract "Previous work demonstrated that a soy-dairy protein blend (PB) prolongs hyperaminoacidemia and muscle protein synthesis in young adults after resistance exercise.We investigated the effect of PB in older adults. We hypothesized that PB would prolong hyperaminoacidemia, enhancing mechanistic target of rapamycin complex 1 (mTORC1) signaling and muscle protein anabolism compared with a whey protein isolate (WPI).This double-blind, randomized controlled trial studied men 55-75 y of age. Subjects consumed 30 g protein from WPI or PB (25% soy, 25% whey, and 50% casein) 1 h after leg extension exercise (8 sets of 10 repetitions at 70% one-repetition maximum). Blood and muscle amino acid concentrations and basal and postexercise muscle protein turnover were measured by using stable isotopic methods. Muscle mTORC1 signaling was assessed by immunoblotting.Both groups increased amino acid concentrations (P < 0.05) and mTORC1 signaling after protein ingestion (P < 0.05). Postexercise fractional synthesis rate (FSR; P ≥ 0.05), fractional breakdown rate (FBR; P ≥ 0.05), and net balance (P = 0.08) did not differ between groups. WPI increased FSR by 67% (mean ± SEM: rest: 0.05% ± 0.01%; postexercise: 0.09% ± 0.01%; P < 0.05), decreased FBR by 46% (rest: 0.17% ± 0.01%; postexercise: 0.09% ± 0.03%; P < 0.05), and made net balance less negative (P < 0.05). PB ingestion did not increase FSR (rest: 0.07% ± 0.03%; postexercise: 0.09% ± 0.01%; P ≥ 0.05), tended to decrease FBR by 42% (rest: 0.25% ± 0.08%; postexercise: 0.15% ± 0.08%; P = 0.08), and made net balance less negative (P < 0.05). Within-group percentage of change differences were not different between groups for FSR, FBR, or net balance (P ≥ 0.05).WPI and PB ingestion after exercise in older men induced similar responses in hyperaminoacidemia, mTORC1 signaling, muscle protein synthesis, and breakdown. These data add new evidence for the use of whey or soy-dairy PBs as targeted nutritional interventions to counteract sarcopenia. This trial was registered at clinicaltrials.gov as NCT01847261." @default.
• W2544388718 created "2016-11-04" @default.
• W2544388718 creator A5002192313 @default.
• W2544388718 creator A5009813082 @default.
• W2544388718 creator A5010641027 @default.
• W2544388718 creator A5014318990 @default.
• W2544388718 creator A5026187694 @default.
• W2544388718 creator A5033969355 @default.
• W2544388718 creator A5037897499 @default.
• W2544388718 creator A5053200427 @default.
• W2544388718 creator A5055863124 @default.
• W2544388718 creator A5056820789 @default.
• W2544388718 creator A5061883359 @default.
• W2544388718 creator A5081593987 @default.
• W2544388718 date "2016-10-26" @default.
• W2544388718 modified "2023-10-11" @default.
• W2544388718 title "Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men" @default.
• W2544388718 cites W1734700698 @default.
• W2544388718 cites W1838896829 @default.
• W2544388718 cites W1895513606 @default.
• W2544388718 cites W1920613397 @default.
• W2544388718 cites W1969332657 @default.
• W2544388718 cites W1976060855 @default.
• W2544388718 cites W2000532682 @default.
• W2544388718 cites W2017754801 @default.
• W2544388718 cites W2024628491 @default.
• W2544388718 cites W2050465461 @default.
• W2544388718 cites W2077623853 @default.
• W2544388718 cites W2085792315 @default.
• W2544388718 cites W2093051972 @default.
• W2544388718 cites W2094064960 @default.
• W2544388718 cites W2096882143 @default.
• W2544388718 cites W2097136222 @default.
• W2544388718 cites W2099210995 @default.
• W2544388718 cites W2100833380 @default.
• W2544388718 cites W2102837285 @default.
• W2544388718 cites W2103134155 @default.
• W2544388718 cites W2105439389 @default.
• W2544388718 cites W2112315916 @default.
• W2544388718 cites W2113426840 @default.
• W2544388718 cites W2114028666 @default.
• W2544388718 cites W2116891450 @default.
• W2544388718 cites W2119448420 @default.
• W2544388718 cites W2119552671 @default.
• W2544388718 cites W2126265811 @default.
• W2544388718 cites W2128583851 @default.
• W2544388718 cites W2132683439 @default.
• W2544388718 cites W2135999406 @default.
• W2544388718 cites W2137789014 @default.
• W2544388718 cites W2140240000 @default.
• W2544388718 cites W2141545521 @default.
• W2544388718 cites W2141893506 @default.
• W2544388718 cites W2145390098 @default.
• W2544388718 cites W2151185613 @default.
• W2544388718 cites W2160605920 @default.
• W2544388718 cites W2162315546 @default.
• W2544388718 cites W2162776437 @default.
• W2544388718 cites W2164957265 @default.
• W2544388718 cites W2165208499 @default.
• W2544388718 cites W2166821055 @default.
• W2544388718 cites W2168338325 @default.
• W2544388718 cites W2285932064 @default.
• W2544388718 doi "https://doi.org/10.3945/jn.116.231159" @default.
• W2544388718 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5118761" @default.
• W2544388718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27798330" @default.
• W2544388718 hasPublicationYear "2016" @default.
• W2544388718 type Work @default.
• W2544388718 sameAs 2544388718 @default.
• W2544388718 citedByCount "46" @default.
• W2544388718 countsByYear W25443887182017 @default.
• W2544388718 countsByYear W25443887182018 @default.
• W2544388718 countsByYear W25443887182019 @default.
• W2544388718 countsByYear W25443887182020 @default.
• W2544388718 countsByYear W25443887182021 @default.
• W2544388718 countsByYear W25443887182022 @default.
• W2544388718 countsByYear W25443887182023 @default.
• W2544388718 crossrefType "journal-article" @default.
• W2544388718 hasAuthorship W2544388718A5002192313 @default.
• W2544388718 hasAuthorship W2544388718A5009813082 @default.
• W2544388718 hasAuthorship W2544388718A5010641027 @default.
• W2544388718 hasAuthorship W2544388718A5014318990 @default.
• W2544388718 hasAuthorship W2544388718A5026187694 @default.
• W2544388718 hasAuthorship W2544388718A5033969355 @default.
• W2544388718 hasAuthorship W2544388718A5037897499 @default.
• W2544388718 hasAuthorship W2544388718A5053200427 @default.
• W2544388718 hasAuthorship W2544388718A5055863124 @default.
• W2544388718 hasAuthorship W2544388718A5056820789 @default.
• W2544388718 hasAuthorship W2544388718A5061883359 @default.
• W2544388718 hasAuthorship W2544388718A5081593987 @default.
• W2544388718 hasBestOaLocation W25443887181 @default.
• W2544388718 hasConcept C1008401 @default.
• W2544388718 hasConcept C126322002 @default.
• W2544388718 hasConcept C134018914 @default.
• W2544388718 hasConcept C185592680 @default.
• W2544388718 hasConcept C193230392 @default.
• W2544388718 hasConcept C2777014122 @default.
• W2544388718 hasConcept C2777897731 @default.
• W2544388718 hasConcept C55493867 @default.

• next